Sverre E. Kjeldsen

TL;DR: Improved insulin sensitivity in hypertensives after additional treatment with angiotensin II‐receptor blocker (ARB) compared with calcium‐channel blocker (CCB) alone may be related to decreased plasma noradrenaline and potential sympatholytic effects.

TL;DR: A detailed analysis of the isoglycaemic hyperinsulinaemic glucose clamp in relation to the time spent in performing the procedure was performed and two series performed by independent investigators on different groups were analysed.

TL;DR: It appears that benefit has been shown in elderly patients for at least one representative agent of several drug classes (i.e. diuretics, beta-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors and angiotENSin receptor antagonists) and initiation of antihypertensive treatment in elderly Patients should follow the general guidelines.

TL;DR: The small number of patients evaluated may have limited the power to detect a difference in outcome, and the difference in carotid plaque index increase between the treatment groups during 3 years of treatment could not be statistically linked to specific treatments in the present substudy.