Author
Swagata Pal
Bio: Swagata Pal is an academic researcher from Indian Institute of Chemical Biology. The author has contributed to research in topics: Termitomyces clypeatus & Sucrase. The author has an hindex of 11, co-authored 25 publications receiving 312 citations.
Topics: Termitomyces clypeatus, Sucrase, Nicotine, Pancreatic islets, Islet
Papers
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TL;DR: This is the first report of a beta-glucosidase enzyme with such a low monomeric unit size that will be useful in synthetic biology to produce complex bioactive glycosides and to avoid chemical hazards.
66 citations
TL;DR: Folic acid and vitamin B12 supplementation can reduce nicotine-induced impairment in glucose homeostasis and apoptosis and damage of pancreatic islet cells by modulating oxidative stress, levels of proinflammatory cytokines, and expression of NF-κB.
Abstract: Context: Nicotine is an abundant and most significant component of cigarette smoke. Epidemiological evidence strongly suggests an association between cigarette smoking and pancreatic injury, although effects of smoking on endocrine pancreas are still controversial.Objective: We examined the impact and underlying mechanisms of action of folic acid and vitamin B12 on nicotine-induced damage in pancreatic islets of rats.Materials and methods: Male Wistar rats were treated with nicotine (3 mg/kg body weight/d, intraperitonealy) with or without folic acid (36 µg/kg body weight/d, orally) and vitamin B12 (0.63 µg/kg body weight/d, orally) for 21 d. Fasting blood glucose, oral glucose tolerance test, HBA1c, insulin, oxidative stress parameters, proinflammatory cytokines, and CRP level were measured. Histological evaluation, TUNEL assay, and immunohistochemical staining of NF-κB and caspase-3 were also performed.Results: Folic acid and vitamin B12 blunted the nicotine-induced impairment in fasting blood g...
31 citations
TL;DR: In this paper, the effects of pretreatment processes on mustard stalk and straw (MSS) with common salt (NaCl) in comparison to hot water and alkali were demonstrated.
30 citations
TL;DR: In carbohydrate-rich samples, protein concentrations should be ascertained by precipitation from crude extracts and resolubilization in a noninterfering buffer, and sugar interference was much higher than expected from sugar molecules' individual contribution.
29 citations
TL;DR: Interestingly less glycosylated cellobiase was resistant towards proteolytic as well as endoglycosidase-H digestion and showed higher stability than native enzyme due to increased aggregation of the protein.
27 citations
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TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.
Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …
33,785 citations
TL;DR: This review summarizes the current knowledge on plant polysaccharide depolymerization by basidiomycete species from diverse habitats and compares these data to those for the most broadly studied ascomycete genus, Aspergillus, to provide insight into specific features of basidiaomycetes with respect to plant poly Saccharide degradation.
Abstract: SUMMARY Basidiomycete fungi subsist on various types of plant material in diverse environments, from living and dead trees and forest litter to crops and grasses and to decaying plant matter in soils. Due to the variation in their natural carbon sources, basidiomycetes have highly varied plant-polysaccharide-degrading capabilities. This topic is not as well studied for basidiomycetes as for ascomycete fungi, which are the main sources of knowledge on fungal plant polysaccharide degradation. Research on plant-biomass-decaying fungi has focused on isolating enzymes for current and future applications, such as for the production of fuels, the food industry, and waste treatment. More recently, genomic studies of basidiomycete fungi have provided a profound view of the plant-biomass-degrading potential of wood-rotting, litter-decomposing, plant-pathogenic, and ectomycorrhizal (ECM) basidiomycetes. This review summarizes the current knowledge on plant polysaccharide depolymerization by basidiomycete species from diverse habitats. In addition, these data are compared to those for the most broadly studied ascomycete genus, Aspergillus, to provide insight into specific features of basidiomycetes with respect to plant polysaccharide degradation.
313 citations
TL;DR: In this article, the authors present a review of the history of the use of essential fatty acids in the context of supplementing with vitamins and like substances, including: Vitamin A. Vitamin D. Vitamin E. Vitamin K. Niacin. Pantothenic acid.
Abstract: Introduction and Historical Considerations. Vitamin A. Vitamin D. Vitamin E. Vitamin K. Thiamin. Riboflavin. Niacin. Vitamin B6. Pantothenic Acid. Biotin. Folacin. Vitamin B12. Choline. Vitamin C. Vitamin-Like Substances. Essential Fatty Acids. Vitamin Supplementation. Bibliography. Appendix. Index.
276 citations
TL;DR: The present review work mainly focuses on various aspects of bio-refinery as a sustainable technology to process lignocellulose 'materials' into value-added products.
271 citations
Journal Article•
214 citations