Swarnima Singh

TL;DR: It is demonstrated that exosomes from mouse and human lung-, liver- and brain-tropic tumour cells fuse preferentially with resident cells at their predicted destination, namely lung fibroblasts and epithelial cells, liver Kupffer cells and brain endothelial cells.

TL;DR: It is shown that PDAC-derived exosomes induce liver pre-metastatic niche formation in naive mice and consequently increase liver metastatic burden and suggests that exosomal MIF primes the liver for metastasis and may be a prognostic marker for the development of PDAC liver metastasis.

TL;DR: Preclinical syngeneic p53 null mouse models of triple-negative breast cancer models are employed to develop a treatment regimen that harnessed the immunostimulatory effects of low-dose cyclophosphamide coupled with the pharmacologic inhibition of TAMs using either a small molecule CSF1R inhibitor or an anti-CSF 1R antibody.

TL;DR: Singh et al. as mentioned in this paper showed that combining chemotherapy and macrophage inhibition in triple negative breast cancer improved T-cell and B-cell Infiltration and Durable Regression.

TL;DR: Carbonated milk beverages are drinks produced by the fermentation process (addition of yeast) and carbonated by mechanical or physical method as discussed by the authors and have different health benefits like gastrointestinal proliferation, anti-bacterial spectrum, an anti-carcinogenic effect due to the presence of lactic acid formed during fermentation.