Author
Syafiqah Saidin
Bio: Syafiqah Saidin is an academic researcher from Universiti Teknologi Malaysia. The author has contributed to research in topics: Materials science & Simulated body fluid. The author has an hindex of 10, co-authored 44 publications receiving 408 citations.
Topics: Materials science, Simulated body fluid, PLGA, Coating, Membrane
Papers
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TL;DR: Most common used inorganic and organic antibacterial agents which have potential to be utilized in biomedical applications are provided, thus, classifying the trends of antibacterial mechanism on Gram-negative and Gram-positive bacteria.
108 citations
TL;DR: Non-cylindrical abutments provided a stable locking mechanism that reduced micromotion, and therefore reduced the occurrence of microgaps, but stress tends to concentrate at the vertices of abutment, which could lead to microfractures and subsequent microgap formation.
96 citations
TL;DR: Characterisation techniques showed that Ag nanoparticles and HA agglomerations were successfully immobilised on the polydopamine film through an element reduction process, which is crucial to prevent bacterial infection during the first stage of implant restoration.
76 citations
TL;DR: This review summarizes the current studies on ethnomedicinal practices, phytochemistry, pharmacological studies and a potential study of Acalypha indica in different locations around the world to provide a useful and basic knowledge platform for anyone interested in gaining information about this plant.
49 citations
TL;DR: A strong beneficial effect of the crosslinked PDA film in immobilizing CHX on bio-inert metal, and these materials are applicable in medical devices.
28 citations
Cited by
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University of Winnipeg1, Manipal Institute of Technology2, Tajik State Medical University3, University of Concepción4, Andrés Bello National University5, Shahid Beheshti University of Medical Sciences and Health Services6, University of Yaoundé7, Universiti Putra Malaysia8, Universiti Teknologi MARA9, University of Milan10, University of Alabama in Huntsville11, Canadian Real Estate Association12, University of Naples Federico II13, Kendall College of Art and Design14, University of Karachi15, Jiroft University16
TL;DR: Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies.
Abstract: Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds.
299 citations
TL;DR: This review assesses the BC main features and emphasis is given to a specific biomedical application: wound dressings, with particular focus on the biochemistry and genetic manipulation of BC.
Abstract: Although several therapeutic approaches are available for wound and burn treatment and much progress has been made in this area, room for improvement still exists, driven by the urgent need of better strategies to accelerate wound healing and recovery, mostly for cases of severe burned patients. Bacterial cellulose (BC) is a biopolymer produced by bacteria with several advantages over vegetal cellulose, such as purity, high porosity, permeability to liquid and gases, elevated water uptake capacity and mechanical robustness. Besides its biocompatibility, BC can be modified in order to acquire antibacterial response and possible local drug delivery features. Due to its intrinsic versatility, BC is the perfect example of a biotechnological response to a clinical problem. In this review, we assess the BC main features and emphasis is given to a specific biomedical application: wound dressings. The production process and the physical-chemical properties that entitle this material to be used as wound dressing namely for burn healing are highlighted. An overview of the most common BC composites and their enhanced properties, in particular physical and biological, is provided, including the different production processes. A particular focus is given to the biochemistry and genetic manipulation of BC. A summary of the current marketed BC-based wound dressing products is presented, and finally, future perspectives for the usage of BC as wound dressing are foreseen.
286 citations
TL;DR: Development of new silane coupling agents, their optimization, and surface treatment methods are in progress to address the long term resin bond durability and are highly important.
268 citations
TL;DR: It is indicated that implant systems using a conical implant-abutment connection, provides better results in terms of abutment fit, stability, and seal performance and these design features could lead to improvements over time versus nonconical connection systems.
Abstract: In this systematic review, we aimed to compare conical versus nonconical implant-abutment connection systems in terms of their in vitro and in vivo performances. An electronic search was performed using PubMed, Embase, and Medline databases with the logical operators: "dental implant" AND "dental abutment" AND ("conical" OR "taper" OR "cone"). Names of the most common conical implant-abutment connection systems were used as additional key words to detect further data. The search was limited to articles published up to November 2012. Recent publications were also searched manually in order to find any relevant studies that might have been missed using the search criteria noted above. Fifty-two studies met the inclusion criteria and were included in this systematic review. As the data and methods, as well as types of implants used was so heterogeneous, this mitigated against the performance of meta-analysis. In vitro studies indicated that conical and nonconical abutments showed sufficient resistance to maximal bending forces and fatigue loading. However, conical abutments showed superiority in terms of seal performance, microgap formation, torque maintenance, and abutment stability. In vivo studies (human and animal) indicated that conical and nonconical systems are comparable in terms of implant success and survival rates with less marginal bone loss around conical connection implants in most cases. This review indicates that implant systems using a conical implant-abutment connection, provides better results in terms of abutment fit, stability, and seal performance. These design features could lead to improvements over time versus nonconical connection systems.
181 citations
TL;DR: T titanium implants showed higher wear at the implant interface following cyclic loading when connected to one-piece zirconia implant abutments compared to titanium abutment, hence damage of the internal implant connection could result in prosthetic failures up to the need of implant removal.
173 citations