T
T. Jacob John
Researcher at Christian Medical College & Hospital
Publications - 193
Citations - 4135
T. Jacob John is an academic researcher from Christian Medical College & Hospital. The author has contributed to research in topics: Poliomyelitis eradication & Vaccination. The author has an hindex of 34, co-authored 187 publications receiving 3924 citations. Previous affiliations of T. Jacob John include Government of India & Indian Council of Medical Research.
Papers
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Journal ArticleDOI
Herd immunity and herd effect: new insights and definitions.
T. Jacob John,Reuben Samuel +1 more
TL;DR: Clear understanding of herd immunity as well as the force of transmission of the corresponding infection will help improve the design of effective and efficient immunisation programmes aimed at control, elimination or eradication of vaccine preventable infectious diseases.
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Continuing challenge of infectious diseases in India
TL;DR: India needs to rethink and revise its health policy to broaden the agenda of disease control, and is recommended to create a functional public health infrastructure shared between central and state governments, with professional leadership and a formally trained public health cadre of personnel who manage an integrated control mechanism of diseases in districts.
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Evaluation of simple clinical signs for the diagnosis of acute lower respiratory tract infection
TL;DR: Increased respiratory rates and history of rapid breathing were found to be sensitive in diagnosis of less severe LRI that did not necessitate admission to the wards, whereas chest retraction was not.
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Immunogenicity of bivalent types 1 and 3 oral poliovirus vaccine: a randomised, double-blind, controlled trial
Roland W. Sutter,T. Jacob John,Hemant Jain,Sharad Agarkhedkar,Padmasani Venkat Ramanan,Harish Verma,Jagadish M. Deshpande,Ajit P Singh,Meghana Sreevatsava,Pradeep Malankar,Anthony H. Burton,Arani Chatterjee,Hamid Jafari,R. Bruce Aylward +13 more
TL;DR: A randomised, double-blind, controlled trial to assess the immunogenicity of a novel bivalent types 1 and 3 oral poliovirus vaccine and the superiority of monovalent type 2 OPV over trivalent OPV, and the non-inferiority of bivalent vaccine compared with mopV1 and mOPV3.
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Etiology of Acute Respiratory Infections in Children in Tropical Southern India
TL;DR: Nasopharyngeal secretions and throat-swab specimens from 809 children less than 6 years old with acute respiratory infection were examined by culture and indirect immunofluorescence for the presence of virus or viral antigen.