T
T. Sokka-Isler
Researcher at University of Eastern Finland
Publications - 32
Citations - 6056
T. Sokka-Isler is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 16 publications receiving 5058 citations.
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Journal ArticleDOI
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
Josef S Smolen,Robert Landewé,Ferdinand C. Breedveld,Maya H Buch,Maya H Buch,Gerd R Burmester,Maxime Dougados,Paul Emery,Paul Emery,Cécile Gaujoux-Viala,Laure Gossec,Jackie L Nam,Jackie L Nam,Sofia Ramiro,Kevin L. Winthrop,Maarten de Wit,Daniel Aletaha,Neil Betteridge,Johannes W. J. Bijlsma,Maarten Boers,Frank Buttgereit,Bernard Combe,Maurizio Cutolo,Nemanja Damjanov,Johanna M. W. Hazes,Marios Kouloumas,Tore K Kvien,Xavier Mariette,Karel Pavelka,Piet L. C. M. van Riel,Andrea Rubbert-Roth,Marieke Scholte-Voshaar,David Scott,T. Sokka-Isler,John B. Wong,Désirée van der Heijde +35 more
TL;DR: These recommendations intend informing rheumatologists, patients, national rheumology societies, hospital officials, social security agencies and regulators about EULAR's most recent consensus on the management of RA, aimed at attaining best outcomes with current therapies.
Journal ArticleDOI
Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force
Josef S Smolen,Ferdinand C. Breedveld,Gerd R Burmester,Vivian P. Bykerk,Maxime Dougados,Paul Emery,Tore K Kvien,M Victoria Navarro-Compán,Susan Oliver,Monika Schoels,Marieke Scholte-Voshaar,Tanja Stamm,Michaela Stoffer,Tsutomu Takeuchi,Daniel Aletaha,Jose Louis Andreu,Martin Aringer,Martin J. Bergman,Neil Betteridge,H. Bijlsma,Harald Burkhardt,Mario H. Cardiel,Bernard Combe,Patrick Durez,João Eurico Fonseca,A. Gibofsky,Juan J. Gomez-Reino,Winfried Graninger,Pekka Hannonen,Boulos Haraoui,Marios Kouloumas,Robert Landewé,Emilio Martín-Mola,Peter Nash,Mikkel Østergaard,Andrew J. K. Östör,Pam Richards,T. Sokka-Isler,Carter Thorne,Athanasios G. Tzioufas,Ronald F van Vollenhoven,Martinus de Wit,Désirée van der Heijde +42 more
TL;DR: The 4 overarching principles and 10 recommendations are based on stronger evidence than before and are supposed to inform patients, rheumatologists and other stakeholders about strategies to reach optimal outcomes of RA.
Journal ArticleDOI
Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial
Merete Lund Hetland,Espen A Haavardsholm,Anna Rudin,Dan Nordström,M. T. Nurmohamed,Bjorn Gudbjornsson,Jon Lampa,Kim Hørslev-Petersen,Till Uhlig,Gerdur Gröndal,Mikkel Østergaard,Marte Schrumpf Heiberg,Jos W. R. Twisk,Kristina Lend,Simon Krabbe,Lise Hyldstrup,Joakim Lindqvist,Anna-Karin H. Ekwall,Kathrine Lederballe Grøn,Meliha C Kapetanovic,F. Faustini,Riitta Tuompo,Tove Lorenzen,Giovanni Cagnotto,Eva Baecklund,Oliver Hendricks,Daisy Vedder,T. Sokka-Isler,Tomas Husmark,Maud Kristine Aga Ljoså,Eli Brodin,Torkell Ellingsen,Annika Soderbergh,Milad Rizk,Åsa Reckner Olsson,Per Larsson,Line Uhrenholt,Søren Andreas Just,David John Stevens,Trine Bay Laurberg,Gunnstein Bakland,Inge C. Olsen,Ronald F van Vollenhoven,Ronald F van Vollenhoven +43 more
TL;DR: The results highlight the efficacy and safety of active conventional treatment based on methotrexate combined with corticosteroids and certification pegol and tocilizumab, but not to abatacept, and show no major differences among the four treatments.
Journal ArticleDOI
Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia.
Paula Savola,Oscar Brück,Thomas Olson,Tiina Kelkka,Markku J Kauppi,Panu E. Kovanen,Soili Kytölä,T. Sokka-Isler,Thomas P. Loughran,Marjatta Leirisalo-Repo,Satu Mustjoki +10 more
TL;DR: Somatic STAT3 mutations and STAT3 activation are as frequent in Felty syndrome as they are in large granular lymphocyte leukemia, and a unified reclassification of these two syndromes is warranted.
Journal ArticleDOI
Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease
Josef S. Smolen,Sabine Collaud Basset,Maarten Boers,Ferdinand C. Breedveld,Christopher J Edwards,Tore K Kvien,Pierre Miossec,T. Sokka-Isler,Ronald van Vollenhoven,Ronald van Vollenhoven,Eric Abadie,Olivier Bruyère,Cyrus Cooper,Cyrus Cooper,Cyrus Cooper,Heidi Mäkinen,Thierry Thomas,Peter Tugwell,Jean-Yves Reginster +18 more
TL;DR: A task force of experts in rheumatoid arthritis and clinical trial methodology was convened to comment on the new draft ‘Guideline on clinical investigation of medicinal products for the treatment of RA’ released by the European Medicines Agency.