T
Taco W. A. Kooij
Researcher at Radboud University Nijmegen
Publications - 52
Citations - 4316
Taco W. A. Kooij is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Plasmodium berghei & Plasmodium falciparum. The author has an hindex of 26, co-authored 49 publications receiving 3890 citations. Previous affiliations of Taco W. A. Kooij include Leiden University & Heidelberg University.
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Journal ArticleDOI
A Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses
Neil Hall,Marianna Karras,J. Dale Raine,Jane M. Carlton,Jane M. Carlton,Jane M. Carlton,Taco W. A. Kooij,Matthew Berriman,Laurence Florens,Christoph S. Janssen,Arnab Pain,Georges K. Christophides,Keith D. James,Kim Rutherford,Barbara Harris,David Harris,Carol Churcher,Michael A. Quail,Doug Ormond,Jon Doggett,Holly E. Trueman,Jacqui Mendoza,Shelby L. Bidwell,Marie Adele Rajandream,Daniel J. Carucci,John R. Yates,Fotis C. Kafatos,Chris J. Janse,Bart Barrell,C. Michael R. Turner,Andrew P. Waters,Robert E. Sinden +31 more
TL;DR: It is observed posttranscriptional gene silencing through translational repression of messenger RNA during sexual development, and a 47-base 3′ untranslated region motif is implicated in this process.
Journal ArticleDOI
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
Jane M. Carlton,Jane M. Carlton,John H. Adams,Joana C. Silva,Shelby L. Bidwell,Hernan Lorenzi,Elisabet Caler,Jonathan Crabtree,Jonathan Crabtree,Samuel V. Angiuoli,Emilio F. Merino,Paolo Amedeo,Qin Cheng,Richard M.R. Coulson,Brendan S. Crabb,Hernando A. del Portillo,Kobby Essien,T. Feldblyum,Carmen Fernandez-Becerra,Paul R. Gilson,Amy H. Gueye,Xiang Guo,Simon Kang’a,Taco W. A. Kooij,Michael Korsinczky,Michael Korsinczky,Esmeralda V. S. Meyer,Vish Nene,Ian T. Paulsen,Owen White,Stuart A. Ralph,Qinghu Ren,Tobias Sargeant,Steven L. Salzberg,Christian J. Stoeckert,Steven A. Sullivan,Marcio Massao Yamamoto,Stephen L. Hoffman,Jennifer R. Wortman,Malcolm J. Gardner,Mary R. Galinski,John W. Barnwell,Claire M. Fraser-Liggett +42 more
TL;DR: The synteny and isochore structure of P. vivax chromosomes are described, and it is shown that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously.
Journal ArticleDOI
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii
Jane M. Carlton,Samuel V. Angiuoli,Bernard B. Suh,Taco W. A. Kooij,Mihaela Pertea,Joana C. Silva,Maria D. Ermolaeva,Jonathan E. Allen,Jeremy D. Selengut,Hean L. Koo,Jeremy Peterson,Mihai Pop,Daniel S. Kosack,Martin Shumway,Shelby L. Bidwell,Shamira J. Shallom,Susan Van Aken,Steven B. Riedmuller,Tamara Feldblyum,Jennifer Cho,John Quackenbush,Martha Sedegah,Azadeh Shoaibi,Leda M. Cummings,Laurence Florens,John R. Yates,J. Dale Raine,Robert E. Sinden,Michael Harris,Deirdre A. Cunningham,Peter R. Preiser,Lawrence W. Bergman,Akhil B. Vaidya,Leo H.M. van Lin,Chris J. Janse,Andrew P. Waters,Hamilton O. Smith,Owen White,Steven L. Salzberg,J. Craig Venter,Claire M. Fraser,Stephen L. Hoffman,Malcolm J. Gardner,Daniel J. Carucci +43 more
TL;DR: This is the first genome sequence of a model eukaryotic parasite, and it provides insight into the use of such systems in the modelling of Plasmodium biology and disease.
Journal ArticleDOI
Ratio-fluorescence microscopy of lipid oxidation in living cells using C11-BODIPY581/591
E.H.W. Pap,Gregor P. C. Drummen,V.J. Winter,Taco W. A. Kooij,P.J. Rijken,Karel W. A. Wirtz,J.A.F. Op den Kamp,W.J. Hage,Jan A. Post +8 more
TL;DR: The data demonstrate that C11‐BODIPY581/591 is a valuable tool to quantify lipid oxidation and anti‐oxidant efficacy in single cells.
Journal ArticleDOI
The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection
Christiaan van Ooij,Pamela A. Tamez,Souvik Bhattacharjee,N. Luisa Hiller,Travis Harrison,Konstantinos Liolios,Taco W. A. Kooij,Jai Ramesar,Bharath Balu,John H. Adams,Andrew P. Waters,Chris J. Janse,Kasturi Haldar +12 more
TL;DR: Genomic screens combined with functional assays provide unexpected and fundamental insights into host remodeling by this major human pathogen, Plasmodium falciparum.