T
Takao Miyata
Researcher at Kumamoto University
Publications - 11
Citations - 3358
Takao Miyata is an academic researcher from Kumamoto University. The author has contributed to research in topics: Insulin & Bradykinin receptor. The author has an hindex of 6, co-authored 11 publications receiving 3261 citations.
Papers
More filters
Journal ArticleDOI
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study.
Yasuo Ohkubo,Hideki Kishikawa,Eiichi Araki,Takao Miyata,S. Isami,S. Motoyoshi,Yujiro Kojima,Naohiko Furuyoshi,Motoaki Shichiri +8 more
TL;DR: In conclusion, intensive glycemic control by multiple insulin injection therapy can delay the onset and the progression of diabetic retinopathy, nephropathy and neuropathy in Japanese patients with NIDDM.
Journal Article
Development of a ferrocene-mediated needle-type glucose sensor covered with newly designed biocompatible membrane, 2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate.
Kenro Nishida,Michiharu Sakakida,Kenshi Ichinose,T. Uemura,M. Uehara,K. Kajiwara,Takao Miyata,M. Shichiri,K Ishihara,N. Nakabayashi +9 more
TL;DR: The ferrocene-mediated needle-type glucose sensor covered with poly(MPC-co-BMA) membrane achieved excellent results in vitro, and it is concluded that this sensor is stable and reliable, as compared to any other glucose sensors developed.
Journal ArticleDOI
Effect on insulin sensitivity of angiotensin converting enzyme inhibitors with or without a sulphydryl group: Bradykinin may improve insulin resistance in dogs and humans
M. Uehara,Hideki Kishikawa,S. Isami,K. Kisanuki,Yasuo Ohkubo,Nobuhiro Miyamura,Takao Miyata,Tomohiko Yano,Motoaki Shichiri +8 more
TL;DR: It is concluded that ACE inhibitors with a sulphydryl group have more potent action on the improvement in insulin sensitivity than those without a sulphytol group.
Journal ArticleDOI
Bradykinin potentiates insulin-stimulated glucose uptake and enhances insulin signal through the bradykinin B2 receptor in dog skeletal muscle and rat L6 myoblasts
Takao Miyata,Tetsuya Taguchi,M. Uehara,Satosi Isami,Hideki Kishikawa,Kengo Kaneko,Eiichi Araki,Motoaki Shichiri +7 more
TL;DR: It is concluded that bradykinin could potentiate the insulin-induced glucose uptake through GLUT4 translocation in dog skeletal muscle and rat L6 myoblasts.
Journal ArticleDOI
Effect of α2-adrenoceptor antagonist on platelet activation during insulin-induced hypoglycaemia in Type 2 (non-insulin-dependent) diabetes mellitus
Haruo Takeda,Hideki Kishikawa,Moritsugu Shinohara,Takao Miyata,Kyoichi Suzaki,Hideo Fukushima,Kenshi Ichinose,Motoaki Shichiri +7 more
TL;DR: It is suggested that plasma epinephrine plays an important role in platelet activation during hypoglycaemia in Type 2 diabetes mellitus, and that the plateletactivation is prevented by α2-adrenoceptor antagonist.