T
Takayoshi Mamiya
Researcher at Meijo University
Publications - 67
Citations - 1884
Takayoshi Mamiya is an academic researcher from Meijo University. The author has contributed to research in topics: Phencyclidine & Dopamine. The author has an hindex of 26, co-authored 67 publications receiving 1678 citations. Previous affiliations of Takayoshi Mamiya include University of Chicago & LSU Health Sciences Center New Orleans.
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Journal ArticleDOI
Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice
Ping Lu,Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Li Bo Zou,Taku Nagai,Masayuki Hiramatsu,Takashi Ikejima,Toshitaka Nabeshima +10 more
TL;DR: The effect of silibinin on the memory impairment and accumulation of oxidative stress induced by Aβ25–35 in mice is examined.
Journal ArticleDOI
[Gly14]‐Humanin improved the learning and memory impairment induced by scopolamine in vivo
Takayoshi Mamiya,Makoto Ukai +1 more
TL;DR: The results suggest that [Gly14]‐humanin is a beneficial drug for the impairment of learning and memory and it modulates the learning andMemory function mediated via cholinergic systems in mice.
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Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.
Shigeru Tomida,Takayoshi Mamiya,Hirotake Sakamaki,Masami Miura,Toshihiko Aosaki,Masao Masuda,Minae Niwa,Tsutomu Kameyama,Junya Kobayashi,Yuka Iwaki,Saki Imai,Akira Ishikawa,Kuniya Abe,Takashi Yoshimura,Toshitaka Nabeshima,Shizufumi Ebihara +15 more
TL;DR: Usp46 affects the immobility in the TST and FST, and it is implicated in the regulation of GABA action.
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Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment
Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Minae Niwa,Hyoung-Chun Kim,Li Bo Zou,Taku Nagai,Kiyofumi Yamada,Takashi Ikejima,Toshitaka Nabeshima +11 more
TL;DR: Silibinin dose-dependently ameliorated the impairment of recognition memory caused by METH treatment in mice and found a correlation between the recognition values and dopamine and serotonin contents of the prefrontal cortex and hippocampus.
Journal ArticleDOI
Silibinin Attenuates Amyloid β25–35 Peptide-Induced Memory Impairments: Implication of Inducible Nitric-Oxide Synthase and Tumor Necrosis Factor-α in Mice
Ping Lu,Takayoshi Mamiya,Lingling Lu,Lingling Lu,Akihiro Mouri,Minae Niwa,Masayuki Hiramatsu,Li Bo Zou,Taku Nagai,Takashi Ikejima,Toshitaka Nabeshima +10 more
TL;DR: It is found that silibinin significantly attenuated memory deficits caused by Aβ25–35 in the cued and contextual fear-conditioning test and may be a potential candidate for an AD medication.