T
Talapady N. Bhat
Researcher at National Institute of Standards and Technology
Publications - 58
Citations - 41548
Talapady N. Bhat is an academic researcher from National Institute of Standards and Technology. The author has contributed to research in topics: Protein Data Bank & Protein Data Bank (RCSB PDB). The author has an hindex of 31, co-authored 58 publications receiving 37067 citations. Previous affiliations of Talapady N. Bhat include Pasteur Institute & New York University.
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Journal ArticleDOI
The Protein Data Bank
Helen M. Berman,John D. Westbrook,Zukang Feng,Gary L. Gilliland,Talapady N. Bhat,Helge Weissig,Ilya N. Shindyalov,Philip E. Bourne +7 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information and plans for the future development of the resource are described.
Journal ArticleDOI
The Protein Data Bank.
Helen M. Berman,Tammy Battistuz,Talapady N. Bhat,Wolfgang F. Bluhm,Philip E. Bourne,Philip E. Bourne,Kyle Burkhardt,Zukang Feng,Gary L. Gilliland,Lisa Iype,Shri Jain,Phoebe Fagan,Jessica Marvin,David Padilla,Veerasamy Ravichandran,Bohdan Schneider,Narmada Thanki,Helge Weissig,John D. Westbrook,Christine Zardecki +19 more
TL;DR: The goals of the PDB are described, the systems in place for data deposition and access, how to obtain further information, and near-term plans for the future development of the resource are described.
Journal ArticleDOI
The Protein Data Bank and the challenge of structural genomics
Helen M. Berman,Talapady N. Bhat,Philip E. Bourne,Zukang Feng,Gary L. Gilliland,Helge Weissig,John D. Westbrook +6 more
TL;DR: The PDB has created systems for the processing, exchange, query, and distribution of data that will enable many aspects of high throughput structural genomics.
Journal ArticleDOI
Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Talapady N. Bhat,Graham A. Bentley,G. Boulot,Mark I. Greene,D Tello,W. Dall'Acqua,Hélène Souchon,F P Schwarz,Roy A. Mariuzza,Roberto J. Poljak +9 more
TL;DR: Structural analysis of the Fv fragment of the anti-hen egg white lysozyme antibody D1.3 reveals a role for solvent molecules in stabilizing the complex and provides a molecular basis for understanding the thermodynamic forces which drive the association reaction.
Journal ArticleDOI
Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
TL;DR: The crystal structure of tyrosyl-tRNA synthetase (EC 6.1.1) from Bacillus stearothermophilus has been refined to a crystallographic R-factor of 22.6% at 2.3 A resolution and the results of site-directed mutagenesis studies are examined in the light of these refined structures.