T
Tamara Lazarević-Pašti
Researcher at University of Belgrade
Publications - 36
Citations - 2255
Tamara Lazarević-Pašti is an academic researcher from University of Belgrade. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 13, co-authored 26 publications receiving 1596 citations.
Papers
More filters
Journal ArticleDOI
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
TL;DR: An overview of toxicology and pharmacology of reversible and irreversible acetylcholinesterase inactivating compounds is presented, with emphasis on oxime reactivators of the inhibited enzyme activity administering as causal drugs after the poisoning.
Journal ArticleDOI
Myeloperoxidase Inhibitors as Potential Drugs.
TL;DR: Various methods for MPO activity inhibition and unfavorable effects of MPO-derived oxidants remodeling will be discussed, and emphasis will be put on various known inhibitors, as well as on newly investigated natural products, which can also inhibitMPO activity.
Journal ArticleDOI
Modulators of Acetylcholinesterase Activity: From Alzheimer's Disease to Anti-Cancer Drugs
TL;DR: A broad range of possible application of different AChE inhibitors as drugs, from well-known anti-Alzheimer's disease drugs to their use in cancer treatment in future are discussed.
Journal ArticleDOI
Chronic administration of fluoxetine or clozapine induces oxidative stress in rat liver: A histopathological study
Jelena Zlatković,Nevena Todorović,Nada Tomanovic,Maja Bošković,Snežana Djordjević,Tamara Lazarević-Pašti,Rick E. Bernardi,Aleksandra Djurdjević,Dragana Filipović +8 more
TL;DR: It is suggested that clozapine appears to have a higher potential to induce liver toxicity than fluoxetine, as demonstrated by the measurement of liver enzymes, oxidative stress and histopathology in rats exposed to chronic social isolation.
Journal ArticleDOI
Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts
Branislav Nastasijević,Tamara Lazarević-Pašti,Suzana Dimitrijević-Branković,Igor A. Pašti,Ana Vujačić,Gordana Joksić,Vesna Vasić +6 more
TL;DR: Among all extracts, the antioxidant capacity of 50% ethanol aqueous extract was the highest, both when measured using the DPPH test, and when using CV, and gentiopicroside has proved to be the strongest inhibitor of MPO, with IC(50)=0.8 μg/ml.