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Ted M. Dawson

Researcher at Johns Hopkins University School of Medicine

Publications -  572
Citations -  106767

Ted M. Dawson is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Neurodegeneration & Parkinson's disease. The author has an hindex of 155, co-authored 537 publications receiving 94434 citations. Previous affiliations of Ted M. Dawson include Eastern Virginia Medical School & National Institute on Drug Abuse.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, +20 more
- 26 Jan 2017 - 
TL;DR: It is shown that activated microglia induce A1 astrocytes by secreting Il-1α, TNF and C1q, and that these cytokines together are necessary and sufficient to induce A2 astroCytes, which are abundant in various human neurodegenerative diseases.
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Lorenzo Galluzzi, +186 more
- 23 Jan 2018 - 
TL;DR: The Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.
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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Lorenzo Galluzzi, +38 more
- 01 Jan 2012 - 
TL;DR: A functional classification of cell death subroutines is proposed that applies to both in vitro and in vivo settings and includes extrinsic apoptosis, caspase-dependent or -independent intrinsic programmed cell death, regulated necrosis, autophagic cell death and mitotic catastrophe.
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Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

Valina L. Dawson, +4 more
- 15 Jul 1991 - 
TL;DR: It is established that NO mediates the neurotoxicity of glutamate and Hemoglobin, which complexes NO, prevents neurotoxic effects of both N-methyl-D-aspartate and sodium nitroprusside.