T
Terri McClanahan
Researcher at Schering-Plough
Publications - 19
Citations - 10298
Terri McClanahan is an academic researcher from Schering-Plough. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 17, co-authored 19 publications receiving 9797 citations.
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Journal ArticleDOI
Involvement of chemokine receptors in breast cancer metastasis.
Anja Müller,Bernhard Homey,Hortensia Soto,Nianfeng Ge,Daniel Catron,Matthew E. Buchanan,Terri McClanahan,Erin Murphy,Wei Yuan,Stephan N. Wagner,Jose Luis Barrera,Alejandro Mohar,Emma Verastegui,Albert Zlotnik +13 more
TL;DR: It is reported that the chemokine receptors CXCR4 and CCR7 are highly expressed in human breast cancer cells, malignant breast tumours and metastases and their respective ligands CXCL12/SDF-1α and CCL21/6Ckine exhibit peak levels of expression in organs representing the first destinations of breast cancer metastasis.
Journal ArticleDOI
Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP
Vassili Soumelis,Pedro A. Reche,Holger Kanzler,Wei Yuan,Gina Edward,Bernhart Homey,Michel Gilliet,Steve Ho,Svetlana Antonenko,Annti Lauerma,Kathleen M. Smith,Daniel M. Gorman,Sandra Zurawski,Jon Abrams,Satish Menon,Terri McClanahan,Rene de Waal-Malefyt,Fernando Bazan,Robert A. Kastelein,Yong-Jun Liu +19 more
TL;DR: It is shown that human thymic stromal lymphopoietin (TSLP) potently activated CD11c+ dendritic cells (DCs) and induced production of the TH2-attracting chemokines TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derivedChemokine; CCL22).
Journal ArticleDOI
Retinoic Acid Early Inducible Genes Define a Ligand Family for the Activating NKG2D Receptor in Mice
Adelheid Cerwenka,Alexander B. H. Bakker,Terri McClanahan,Janet Wagner,Jun Wu,Joseph H. Phillips,Lewis L. Lanier +6 more
TL;DR: A family of GPI-anchored cell surface proteins that function as ligands for the mouse activating NKG2D receptor on NK and T cells are identified and may play an important role in innate and adaptive immunity.
Journal ArticleDOI
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
Charles H. Hannum,Janice Culpepper,D. Campbell,Terri McClanahan,Sandra Zurawski,Robert A. Kastelein,J. F. Bazan,S. Hudak,J. Wagner,Jeanine D. Mattson,J. Luh,G. Duda,N. Martina,D Peterson,S. Menon,A. Shanafelt,Marcus O. Muench,G. Kelner,Reiko Namikawa,D. Rennick,Maria Grazia Roncarolo,Albert Zlotnik,O. Rosnet,P. Dubreuil,Daniel Birnbaum,Frank Lee +25 more
TL;DR: The purified ligand enhances the response of mouse stem cells and a primitive human progenitor cell population to other growth factors such as interleukins IL-3 and IL-6 and to granulocyte-macrophage colony-stimulating factor, and also stimulates fetal thymocytes.
Journal ArticleDOI
Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.
Gavin J. Wright,Holly Cherwinski,Mildred Foster-Cuevas,Gary Brooke,M J Puklavec,M. Bigler,Yaoli Song,Maria C. Jenmalm,Daniel M. Gorman,Terri McClanahan,Man-ru Liu,Marion H. Brown,Jonathon D. Sedgwick,Joseph H. Phillips,A. Neil Barclay +14 more
TL;DR: The first characterization of human CD200R (hCD200R) is reported and its binding characteristics to hCD200 are defined, and two mCD200 receptor-like family members were shown to pair with the activatory adaptor protein, DAP12, suggesting that these receptors would transmit strong activating signals in contrast to the apparent inhibitory signal delivered by triggering the CD 200R.