Tetsu Tanaka

Bio: Tetsu Tanaka is an academic researcher from Tohoku University. The author has contributed to research in topics: Wafer & Chip. The author has an hindex of 38, co-authored 406 publications receiving 10375 citations. Previous affiliations of Tetsu Tanaka include NTT DoCoMo & Tokyo Medical and Dental University.

Reduction of magnetic grain size of perpendicular recording media with CoCrW seed layer

Abstract: We report the use of CoCrW seed layer (SL) for making the fine grain granular structure and high crystalline orientation of CoCrPt-oxide magnetic recording layer. It is found that CoCrW SL should be of amorphouslike structure to make fine grain of CoCrPt-oxide magnetic layer. Moreover, the smooth surface of CoCrW SL provides high crystalline orientation of the CoCrPt-oxide magnetic layer.

Room-Temperature Cu Direct Bonding Technology Enabling 3D Integration with Micro-LEDs

Abstract: This paper describes Cu direct bonding at room temperature for wearable micro-LED display. Still, the conventional bonding methods of micro-LEDs with solder micro-bumps have heat problems during bonding and difficulty achieving a narrow pitch. Using a unique method developed in this paper, it is possible to bond micro-LEDs to a 3D-IC chiplet without using the micro-bumps. Here, The 30 x 30 arrays of 0.1-mm-square blue micro-LEDs are assembled, bonded, and interconnected on a sapphire substrate through electroplated Cu, and successful emission from the blue micro-LEDs is confirmed. The bonding strength of the room-temperature Cu direct bonding with the micro-LEDs and a yield enhancement technique is also described. Finally, we emphasize the high potential of massively parallel chiplet self-assembly using liquid surface tension.

Design and evaluation of area-efficient and wide-range impedance analysis circuit for multichannel high-quality brain signal recording system

Abstract: To enable chronic and stable neural recording, we have been developing an implantable multichannel neural recording system with impedance analysis functions. One of the important things for high-quality neural signal recording is to maintain well interfaces between recording electrodes and tissues. We have proposed an impedance analysis circuit with a very small circuit area, which is implemented in a multichannel neural recording and stimulating system. In this paper, we focused on the design of an impedance analysis circuit configuration and the evaluation of a minimal voltage measurement unit. The proposed circuit has a very small circuit area of 0.23 mm2 designed with 0.18 µm CMOS technology and can measure interface impedances between recording electrodes and tissues in ultrawide ranges from 100 Ω to 10 MΩ. In addition, we also successfully acquired interface impedances using the proposed circuit in agarose gel experiments.

Process and device technologies for high-performance 0.13 μm FCRAM

Abstract: We have developed a novel integration scheme for FCRAM cores using a high-dielectric capacitor technology and low-temperature process technology so we can scale the design rule towards 0.13 pm and improve device performance. Ru/Ta 2 O 5 /Ru capacitor technology, which can provide a dielectric constant as high as 70 and an SiO 2 -equivalent thickness of 0.7 nm, has been established combined with a robust cylinder electrode fabrication process using a TiN liner. A self-aligned storage-node contact fabrication process with low-temperature (600°C) Si 3 N 4 deposition improves the transistor performance by more than 10%. These technologies have been applied to a 0.13 μm-generation device, and the functionality of this device has been confirmed. Also, this paper demonstrates the scalability of these technologies to the 0.1 pm generation.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Abstract: Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tuberculosis, H37Rv, has been determined and analysed in order to improve our understanding of the biology of this slow-growing pathogen and to help the conception of new prophylactic and therapeutic interventions. The genome comprises 4,411,529 base pairs, contains around 4,000 genes, and has a very high guanine + cytosine content that is reflected in the biased amino-acid content of the proteins. M. tuberculosis differs radically from other bacteria in that a very large portion of its coding capacity is devoted to the production of enzymes involved in lipogenesis and lipolysis, and to two new families of glycine-rich proteins with a repetitive structure that may represent a source of antigenic variation.

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Abstract: BackgroundExperimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. MethodsWe conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. ResultsAt 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in t...

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.

Abstract: Pseudomonas aeruginosa is a ubiquitous environmental bacterium that is one of the top three causes of opportunistic human infections. A major factor in its prominence as a pathogen is its intrinsic resistance to antibiotics and disinfectants. Here we report the complete sequence of P. aeruginosa strain PAO1. At 6.3 million base pairs, this is the largest bacterial genome sequenced, and the sequence provides insights into the basis of the versatility and intrinsic drug resistance of P. aeruginosa. Consistent with its larger genome size and environmental adaptability, P. aeruginosa contains the highest proportion of regulatory genes observed for a bacterial genome and a large number of genes involved in the catabolism, transport and efflux of organic compounds as well as four potential chemotaxis systems. We propose that the size and complexity of the P. aeruginosa genome reflect an evolutionary adaptation permitting it to thrive in diverse environments and resist the effects of a variety of antimicrobial substances.