Tetsu Tanaka

Bio: Tetsu Tanaka is an academic researcher from Tohoku University. The author has contributed to research in topics: Wafer & Chip. The author has an hindex of 38, co-authored 406 publications receiving 10375 citations. Previous affiliations of Tetsu Tanaka include NTT DoCoMo & Tokyo Medical and Dental University.

Effect of readout magnetic-field direction on trilayer magnetically induced super resolution media (abstract)

Abstract: Among the proposed magnetically induced super resolution media, double-mask rear aperture detection (RAD) has the greatest potential for use in high-density land/groove recording.1 We proposed a trilayer double-mask RAD media that does not require a large initializing magnetic field.2 In this paper, we report the land/groove recording on the trilayer media for a 0.4 μm mark length and 0.7 μm track pitch. We found that crosstalk drastically changed depending on the direction of the readout magnetic field, and that the crosswrite is related to crosstalk. When applying the readout magnetic field in the erasing direction, the value of crosstalk was about −25 dB and a large crosswrite effect was observed. Conversely, the crosstalk was below −45 dB and no crosswrite effect was observed when applying the magnetic field in the writing direction. CNRs had almost the same value of 48 dB for both the above cases. To investigate the mask formation while applying the readout field in the writing direction, we precisely observed the wave form of the isolated marks. The carrier level rose twice with increasing readout field. However, the position of the leading edge mainly changed when increasing the field. We think that the low crosstalk is attributable to the enhancement of the front mask area. The trilayer media enables an areal density of 3 Gbit/in.2

Memory Characterization of MOS Memory Device with High Density Self-Assembled Tungsten Nanodots Floating Gate and HfO 2 Blocking Dielectric

Abstract: Tungsten Nanodots Floating Gate and HfO2 Blocking Dielectric Yanli Pei, Masahiko Nishijima, Takafumi Fukushima, Tetsu Tanaka and Mitsumasa Koyanagi International Advanced Research and Education Organization, Tohoku University 6-6-03 Aza-Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan Phone: +81-22-795-4031, E-mail: sdlab@sd.mech.tohoku.ac.jp 2 Institute for Materials Research, Tohoku University Dept. of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University

Efficacy of Pericardial Drainage in Annular Rupture and Periaortic Hematoma After Transcatheter Aortic Valve Replacement.

Abstract: Received January 30, 2018; revised manuscript received May 1, 2018; accepted May 17, 2018; released online June 22, 2018 Time for primary review: 21 days Division of Cardiology (T.T., K.Y., T.O., K.S., K.T.), Division of Cardiovascular Surgery (A.O., S.M.), Division of Anesthesia (M.Y.), Mitsui Memorial Hospital, Tokyo, Japan Mailing address: Kazuyuki Yahagi, MD, Division of Cardiology, Mitsui Memorial Hospital, 1 Kanda-Izumi-cho, Chiyoda-ku, Tokyo 101-8643, Japan. E-mail: yyahakazu@gmail.com ISSN-1346-9843 All rights are reserved to the Japanese Circulation Society. For permissions, please e-mail: cj@j-circ.or.jp Efficacy of Pericardial Drainage in Annular Rupture and Periaortic Hematoma After Transcatheter Aortic Valve Replacement

3D hetero-integration technology with backside TSV and reliability challenges

Abstract: Recently, hetero-integrated system (3-D super chip) involving memory, processor, power ICs, sensor, and photonic circuits has attracted attention owing to its high performance, highspeed communication, multi-functionality, and low power consumption . However, heterointegration of devices with different functions has many technical challenges owing to various types of size, thickness, and substrate because they were fabricated by different technologies. In addition, current 3-D integration technologies have another challenge such as high manufacturing cost and long prototyping time to achieve 3-D super chip. To realize 3-D super-chip with low-cost, high flexibility, and rapid prototyping time, we proposed die-level 3-D hetero-integration technology with fine-size backside TSV. Commercially available 2-D chips with different functions and sizes could be processed and integrated in die-level. To fabricate 3-D super chip, each functional chip should be thinned to 10-50μm thickness. However, the ultra-thin nature of Si substrate leads to several problems such as weak mechanical strength, warping, local deformation, and residual stress in the stacked die. In addition, the large CTE difference between Si substrate and Cu TSV and μ-bump is posing risks of undesired thermo-mechanical stress generation and Cu contamination. In this paper, we describe new 3-D heterointegration technology with backside TSV for realizing 3-D super chip with low-cost, high flexibility, and rapid prototyping time and address our attention on some of the most potent reliability issues such as thermo-mechanical stress, crystal defects, and Cu contamination introduced in 3-D integration processes.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Abstract: Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tuberculosis, H37Rv, has been determined and analysed in order to improve our understanding of the biology of this slow-growing pathogen and to help the conception of new prophylactic and therapeutic interventions. The genome comprises 4,411,529 base pairs, contains around 4,000 genes, and has a very high guanine + cytosine content that is reflected in the biased amino-acid content of the proteins. M. tuberculosis differs radically from other bacteria in that a very large portion of its coding capacity is devoted to the production of enzymes involved in lipogenesis and lipolysis, and to two new families of glycine-rich proteins with a repetitive structure that may represent a source of antigenic variation.

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Abstract: BackgroundExperimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. MethodsWe conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. ResultsAt 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in t...

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.

Abstract: Pseudomonas aeruginosa is a ubiquitous environmental bacterium that is one of the top three causes of opportunistic human infections. A major factor in its prominence as a pathogen is its intrinsic resistance to antibiotics and disinfectants. Here we report the complete sequence of P. aeruginosa strain PAO1. At 6.3 million base pairs, this is the largest bacterial genome sequenced, and the sequence provides insights into the basis of the versatility and intrinsic drug resistance of P. aeruginosa. Consistent with its larger genome size and environmental adaptability, P. aeruginosa contains the highest proportion of regulatory genes observed for a bacterial genome and a large number of genes involved in the catabolism, transport and efflux of organic compounds as well as four potential chemotaxis systems. We propose that the size and complexity of the P. aeruginosa genome reflect an evolutionary adaptation permitting it to thrive in diverse environments and resist the effects of a variety of antimicrobial substances.