T
Thais Fernanda de Campos Fraga-Silva
Researcher at University of São Paulo
Publications - 64
Citations - 640
Thais Fernanda de Campos Fraga-Silva is an academic researcher from University of São Paulo. The author has contributed to research in topics: Medicine & Experimental autoimmune encephalomyelitis. The author has an hindex of 10, co-authored 45 publications receiving 326 citations. Previous affiliations of Thais Fernanda de Campos Fraga-Silva include Sao Paulo State University.
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Journal ArticleDOI
Treatment with Vitamin D/MOG Association Suppresses Experimental Autoimmune Encephalomyelitis.
Fernanda Chiuso-Minicucci,Larissa Lumi Watanabe Ishikawa,Luiza Ayumi Nishiyama Mimura,Thais Fernanda de Campos Fraga-Silva,Thais Graziela Donegá França,Sofia Fernanda Gonçalves Zorzella-Pezavento,Camila Marques,Maura Rosane Valerio Ikoma,Alexandrina Sartori +8 more
TL;DR: The association of myelin oligodendrocyte glycoprotein (MOG) with 1,25(OH) 2D3 was able to control EAE development and determined significant reduction in EAE incidence and in clinical scores.
Journal ArticleDOI
Vitamin D Deficiency and Rheumatoid Arthritis.
Larissa Lumi Watanabe Ishikawa,Priscila Maria Colavite,Thais Fernanda de Campos Fraga-Silva,Luiza Ayumi Nishiyama Mimura,Thais Graziela Donegá França,Sofia Fernanda Gonçalves Zorzella-Pezavento,Fernanda Chiuso-Minicucci,Larissa Doddi Marcolino,Marcimara Penitenti,Maura Rosane Valerio Ikoma,Alexandrina Sartori +10 more
TL;DR: Results suggest that VitD3 played a role as a tolerogenic adjuvant by down-modulating the course of experimental RA, and further investigations will reveal its plausible use in human RA.
Journal ArticleDOI
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage
Tiago J. Costa,Simone R. Potje,Thais Fernanda de Campos Fraga-Silva,Julio Alves Silva-Neto,Paula R. Barros,Daniel N.S. Rodrigues,Mirele R. Machado,Ronaldo B. Martins,Rosangela Aparecida Santos-Eichler,Maira N. Benatti,Keyla Santos Guedes de Sá,Carlos Eduardo L. Almado,Italo A. Castro,Marjorie Cornejo Pontelli,Leonardo La Serra,Fernando S. Carneiro,Christiane Becari,Paulo Louzada-Junior,Renê Donizeti Ribeiro de Oliveira,Dario S. Zamboni,Eurico Arruda,Maria Auxiliadora-Martins,Fernanda R. Giachini,Vânia Luiza Deperon Bonato,Natasha E. Zachara,Gisele Facholi Bomfim,Rita C. Tostes +26 more
TL;DR: In this paper, the involvement of TLR9 in SARS-Cov-2-induced endothelial dysfunction and potential contribution to cardiovascular complications in COVID-19 have not been demonstrated.
Journal ArticleDOI
Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients.
Simone R. Potje,Tiago J. Costa,Thais Fernanda de Campos Fraga-Silva,Ronaldo B. Martins,Maira N. Benatti,Carlos E.L. Almado,Keyla Santos Guedes de Sá,Vânia Luiza Deperon Bonato,Eurico Arruda,Paulo Louzada-Junior,Renê Donizeti Ribeiro de Oliveira,Dario S. Zamboni,Christiane Becari,Maria Auxiliadora-Martins,Rita C. Tostes +14 more
TL;DR: In this paper, the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on endothelial glycocalyx degradation were investigated in a cohort of 20 hospitalized patients with a confirmed COVID-19 diagnosis and healthy subjects were enrolled in this study.
Journal ArticleDOI
Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation.
Larissa Ragozo Cardoso de Oliveira,Luiza Ayumi Nishiyama Mimura,Thais Fernanda de Campos Fraga-Silva,Larissa Lumi Watanabe Ishikawa,Ana Angélica Henrique Fernandes,Sofia Fernanda Gonçalves Zorzella-Pezavento,Alexandrina Sartori +6 more
TL;DR: It is indicated that early intervention with 1,25-dihydroxyvitamin D3 can control the neuroinflammatory process that is the hallmark of EAE and MS immunopathogenesis and should thus be explored as an adjunct therapy for MS patients.