T
Thangavel Alphonse Thanaraj
Researcher at European Bioinformatics Institute
Publications - 74
Citations - 3815
Thangavel Alphonse Thanaraj is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 21, co-authored 57 publications receiving 3122 citations. Previous affiliations of Thangavel Alphonse Thanaraj include Polaris Industries & Wellcome Trust.
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Journal ArticleDOI
Function of alternative splicing.
Stefan Stamm,Shani Ben-Ari,Ilona Rafalska,Yesheng Tang,Zhaiyi Zhang,Debra Toiber,Thangavel Alphonse Thanaraj,Hermona Soreq +7 more
TL;DR: Evidence is now accumulating that alternative splicing coordinates physiologically meaningful changes in protein isoform expression and is a key mechanism to generate the complex proteome of multicellular organisms.
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ASD: a bioinformatics resource on alternative splicing
Stefan Stamm,Jean-Jack M Riethoven,Vincent Le Texier,Chellappa Gopalakrishnan,Vasudev Kumanduri,Yesheng Tang,Nuno L. Barbosa-Morais,Thangavel Alphonse Thanaraj +7 more
TL;DR: ASD includes a workbench, which is an analysis tool that enables users to carry out splicing related analysis such as characterization of introns for various splicing signals, identification of splicing regulatory elements on a given RNA sequence, prediction of putative exons and prediction ofPutative translation start codons.
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ASD: the Alternative Splicing Database.
Thangavel Alphonse Thanaraj,Stefan Stamm,Francis Clark,Jean-Jack M Riethoven,Vincent Le Texier,Juha Muilu +5 more
TL;DR: A database of computationally delineated alternative splice events as seen in alignments of EST/cDNA sequences with genome sequences, and a database of alternatively spliced exons collected from literature are presented.
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Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human
TL;DR: It is found that over one-third of human exons can translate in more than one frame, and that this is highly correlated with G+C content.
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The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target.
Mohamed Abu-Farha,Thangavel Alphonse Thanaraj,Mohammad Qaddoumi,Anwar M. Hashem,Jehad Abubaker,Fahd Al-Mulla +5 more
TL;DR: The role of lipid metabolism in viral infection as well as the possibility of targeting lipid metabolism to interfere with the viral life cycle are discussed.