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Theoharis C. Theoharides
Researcher at Tufts University
Publications - 487
Citations - 33374
Theoharis C. Theoharides is an academic researcher from Tufts University. The author has contributed to research in topics: Mast cell & Inflammation. The author has an hindex of 85, co-authored 464 publications receiving 30490 citations. Previous affiliations of Theoharis C. Theoharides include University of Glasgow & National and Kapodistrian University of Athens.
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Journal Article
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
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Mast cells and inflammation
Theoharis C. Theoharides,Konstantinos-Dionysios Alysandratos,Asimenia Angelidou,Danae A. Delivanis,Nikolaos Sismanopoulos,Bodi Zhang,Shahrzad Asadi,Magdalini Vasiadi,Zuyi Weng,Alexandra Miniati,Dimitrios Kalogeromitros +10 more
TL;DR: Understanding selective release of mediators could explain how mast cells participate in numerous diverse biologic processes, and how they exert both immunostimulatory and immunosuppressive actions.
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Critical role of mast cells in inflammatory diseases and the effect of acute stress
TL;DR: Findings can help understand a variety of sterile inflammatory conditions, such as multiple sclerosis, migraines, inflammatory arthritis, atopic dermatitis, coronary inflammation, interstitial cystitis and irritable bowel syndrome, in which mast cells are activated without allergic degranulation.
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Gut-Microbiota-Brain Axis and Its Effect on Neuropsychiatric Disorders With Suspected Immune Dysregulation
Anastasia I. Petra,Smaro Panagiotidou,Erifili Hatziagelaki,Julia M. Stewart,Pio Conti,Theoharis C. Theoharides +5 more
TL;DR: Recognition of the relationship between the MGB axis and the neuroimmune systems provides a novel approach for better understanding and management of these disorders.
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Corticotropin-Releasing Hormone Induces Skin Mast Cell Degranulation and Increased Vascular Permeability, A Possible Explanation for Its Proinflammatory Effects
Theoharis C. Theoharides,Leena K. Singh,William Boucher,Xinzhu Pang,Richard Letourneau,Elizabeth Webster,George P. Chrousos +6 more
TL;DR: Intradermal administration of rat/human CRH in the rat induced mast cell degranulation and increased capillary permeability in a dose-dependent fashion and systemic administration of antalarmin prevented vascular permeability only by CRH and not by compound 48/80 or SP.