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Thiago Luiz de Paula Castro
Researcher at Federal University of Bahia
Publications - 36
Citations - 926
Thiago Luiz de Paula Castro is an academic researcher from Federal University of Bahia. The author has contributed to research in topics: Corynebacterium pseudotuberculosis & Caseous lymphadenitis. The author has an hindex of 13, co-authored 33 publications receiving 729 citations. Previous affiliations of Thiago Luiz de Paula Castro include Universidade Federal de Minas Gerais.
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Journal ArticleDOI
Two-Component Signal Transduction Systems of Pathogenic Bacteria As Targets for Antimicrobial Therapy: An Overview.
Sandeep Tiwari,Syed Babar Jamal,Syed Shah Hassan,Syed Shah Hassan,Paulo V. S. D. de Carvalho,Sintia Almeida,Debmalya Barh,Preetam Ghosh,Artur Silva,Thiago Luiz de Paula Castro,Thiago Luiz de Paula Castro,Vasco Azevedo +11 more
TL;DR: Some of the characteristics of the bacterial TCSs and their involvement in virulence and antibiotic resistance are listed and inhibitors that have been reported to target T CSs in pathogenic bacteria are discussed.
Journal ArticleDOI
Multiplex PCR assay for identification of Corynebacterium pseudotuberculosis from pure cultures and for rapid detection of this pathogen in clinical samples
Luis G.C. Pacheco,Roberta Ribas Pena,Thiago Luiz de Paula Castro,Fernanda Alves Dorella,Robson Bahia,Renato Carminati,Marcílio N. L. Frota,Sergio C. Oliveira,Roberto Meyer,Francisco Selmo Fernandes Alves,Anderson Miyoshi,Vasco Azevedo +11 more
TL;DR: The developed assay significantly improves rapid C. pseudotuberculosis detection and could supersede bacteriological culture for microbiological and epidemiological diagnosis of CLA.
Journal ArticleDOI
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains.
Jeronimo C. Ruiz,Vivian D'Afonseca,Artur Silva,Amjad Ali,Anne Cybelle Pinto,Anderson Rodrigues dos Santos,Aryanne A. M. C. Rocha,Débora de Oliveira Lopes,Fernanda Alves Dorella,Luis G.C. Pacheco,Luis G.C. Pacheco,Marcília P. Costa,Meritxell Zurita Turk,Núbia Seyffert,Pablo M. R. O. Moraes,Siomar de Castro Soares,Sintia Almeida,Thiago Luiz de Paula Castro,Vinicius A. C. Abreu,Eva Trost,Jan Baumbach,Andreas Tauch,Maria Paula Cruz Schneider,John A. McCulloch,Louise Cerdeira,Rommel Thiago Jucá Ramos,Adhemar Zerlotini,Anderson J. Dominitini,Daniela de Melo Resende,Daniela de Melo Resende,Elisângela Monteiro Coser,Luciana M. Oliveira,André Luiz Pedrosa,Carlos Ueira Vieira,Claudia Teixeira Guimarães,Daniela C. Bartholomeu,Diana Oliveira,Fabrício R. Santos,Élida Mara Leite Rabelo,Francisco Pereira Lobo,Glória Regina Franco,Ana Flávia D.V. Costa,Ieso de Miranda Castro,Sílvia Regina Costa Dias,Jesus Aparecido Ferro,José Miguel Ortega,Luciano Vilela Paiva,Luiz Ricardo Goulart,Juliana Franco Almeida,Maria Inês Tiraboschi Ferro,Newton Portilho Carneiro,Paula R. K. Falcão,Priscila Grynberg,Santuza M. R. Teixeira,Sérgio Hermínio Brommonschenkel,Sergio C. Oliveira,Roberto Meyer,Robert J. Moore,Anderson Miyoshi,Guilherme Oliveira,Guilherme Oliveira,Vasco Azevedo +61 more
TL;DR: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenic pathways used by this pathogen in the infection process.
Journal ArticleDOI
Exoproteome and Secretome Derived Broad Spectrum Novel Drug and Vaccine Candidates in Vibrio cholerae Targeted by Piper betel Derived Compounds
Debmalya Barh,Neha Barve,Krishna Kant Gupta,Sudha Chandra,Neha Jain,Sandeep Tiwari,Nidia León-Sicairos,Adrian Canizalez-Roman,Anderson Rodrigues dos Santos,Syed Shah Hassan,Sintia Almeida,Rommel Thiago Jucá Ramos,Vinicius A. C. Abreu,Adriana Ribeiro Carneiro,Siomar de Castro Soares,Thiago Luiz de Paula Castro,Anderson Miyoshi,Artur Silva,Anil Kumar,Amarendra Narayan Misra,Amarendra Narayan Misra,Kenneth Blum,Kenneth Blum,Eric R. Braverman,Vasco Azevedo +24 more
TL;DR: Preliminary validation suggests that three peptide vaccine candidates that have high potential to induce both B- and T-cell-mediated immune responses from the authors' identified two dual targets are highly effective against Vibrio cholerae.
Journal ArticleDOI
A combined approach for comparative exoproteome analysis of Corynebacterium pseudotuberculosis
Luis G.C. Pacheco,Luis G.C. Pacheco,Susan E. Slade,Núbia Seyffert,Anderson Rodrigues dos Santos,Thiago Luiz de Paula Castro,Wanderson M. Silva,Agenor Valadares Santos,Simone Gonçalves dos Santos,Luiz de Macêdo Farias,Maria Auxiliadora Roque de Carvalho,Adriano Monteiro de Castro Pimenta,Roberto Meyer,Artur Silva,James H. Scrivens,Sergio C. Oliveira,Anderson Miyoshi,Christopher G. Dowson,Vasco Azevedo +18 more
TL;DR: The results presented here compose the most comprehensive coverage of the exoproteome of a corynebacterial species so far, and evidence could be found for probable non-classical export of most of the remaining proteins.