T
Thierry Malfroot
Researcher at Pennsylvania State University
Publications - 14
Citations - 382
Thierry Malfroot is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Chloroformate & Alkyl. The author has an hindex of 4, co-authored 14 publications receiving 367 citations.
Papers
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Journal ArticleDOI
A new reagent for the selective, high-yield N-dealkylation of tertiary amines: improved syntheses of naltrexone and nalbuphine
Journal ArticleDOI
2,2′-carbonyl-bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine): I-A new reagent for the preparation of carbamates and amides, application to the synthesis of dipeptides.
Michel Denarie,Denis Grehouillat,Thierry Malfroot,Jean-Pierre Senet,Gérard Sennyey,Patrick Wolf +5 more
TL;DR: In this article, 2,2′-Carbonyl bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine) was prepared and used for the synthesis of various carbamates and dipeptides.
Journal ArticleDOI
2,2-Dichlorovinyl chloroformate
TL;DR: In this article, 2,2-dichlorovinyl chloroformate (2a) has been shown to be stable but also an active acylating agent.
Journal ArticleDOI
An efficient synthesis of some substituted vinylic chloroformates: reaction scope and limitations
TL;DR: In this paper, 2,2-Dichlorovinyl chloroformate is isolated in 50% distilled yield when chloral is treated with phosgene and zinc dust in 2:1 methyl acetate/ether.
Patent
2,2'-Carbonylbis(4-alkyl-1,2,4-oxadiazolidine-3,5-diones), process for their preparation and their use as synthetic intermediates in the presence of carbamates
TL;DR: In this paper, a new compound of formula I is prepared by reaction, in solvent medium, of an oxadiazolidinedinedione of formula II with phosgene.