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Thomas A. d’Amato

Researcher at University of Pittsburgh

Publications -  12
Citations -  827

Thomas A. d’Amato is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Drug resistance & Lung cancer. The author has an hindex of 10, co-authored 12 publications receiving 754 citations. Previous affiliations of Thomas A. d’Amato include Allegheny General Hospital.

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Anatomic Segmentectomy in the Treatment of Stage I Non-Small Cell Lung Cancer

TL;DR: Anatomic segmentectomy outcomes compare favorably with standard lobectomy for stage I NSCLC and Margin/tumor ratios exceeding 1 were associated with a significant reduction in recurrence rates compared with ratios of less than 1, which should be considered as primary therapy when such margins are not obtainable with segmentectomy in the good-risk patient.
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Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis.

TL;DR: High VEGF expression, tumor size, and angiolymphatic invasion emerged as three independent factors predicting worsening prognosis using multivariate analysis.
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Minimally invasive resection of benign esophageal tumors.

TL;DR: Minimally invasive resection of benign esophageal tumors is technically safe and associated with a shorter length of stay compared with open approaches, and the subsequent development of reflux may be related to the esophagal myotomy required for resection.
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Intraoperative 125I brachytherapy for high-risk stage I non-small cell lung carcinoma

TL;DR: Review of early data suggests that intraoperative 125I vicryl mesh brachytherapy in high-risk Stage I NSCLC is potentially effective and well tolerated, with no significant decline in measurable pulmonary function studies and no increase in postoperative complications.
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Prevalence of In Vitro Extreme Chemotherapy Resistance in Resected Nonsmall-Cell Lung Cancer

TL;DR: Chemotherapy resistance is prevalent among NSCLC clinical cell cultures, and the use of viable tumor culture for in vitro chemoresistance testing should be considered when formulating a plan of adjuvant therapy for resected NSCLCs.