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Thomas A. Wichelhaus

Researcher at Goethe University Frankfurt

Publications -  126
Citations -  4447

Thomas A. Wichelhaus is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Staphylococcus aureus & Medicine. The author has an hindex of 34, co-authored 113 publications receiving 3881 citations.

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Nanocrystalline hydroxyapatite and calcium sulphate as biodegradable composite carrier material for local delivery of antibiotics in bone infections.

Michael Rauschmann, +6 more
- 01 May 2005 - 
TL;DR: PerOssal exhibits excellent properties regarding resorption, biocompatibility, and antibiotic release and calcium sulphate showed cytotoxic effects in two out of four tests.
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NDM-2 carbapenemase in Acinetobacter baumannii from Egypt

Martin Kaase, +5 more
- 21 Mar 2011 - 
TL;DR: A variant of NDM-1 that had a C to G substitution at position 82 resulting in an amino acid substitution of proline to alanine at position 28 was revealed, which further underlines the spread of N DM carbapenemases in A. baumannii and theSpread of the corresponding gene in the Middle East.
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Effects of subinhibitory concentrations of antibiotics on alpha-toxin (hla) gene expression of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates.

Knut Ohlsen, +5 more
- 01 Nov 1998 - 
TL;DR: The results indicate that the novel gene fusion technique is a useful tool for studying the modulation of virulence gene expression by antibiotics, and suggest that the effects of certain antibiotics on virulence properties may be relevant for the management of S. aureus infections.
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Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007

Yvonne Pfeifer, +8 more
- 01 Sep 2011 - 
TL;DR: The variability of the genetic environment of bla(NDM-1) likely facilitates the rapid dissemination of this gene within many Gram-negative bacterial species.
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Prevalence and Clinical Significance of Staphylococcus aureus Small-Colony Variants in Cystic Fibrosis Lung Disease

Silke Besier, +6 more
- 01 Jan 2007 - 
TL;DR: The independent risk factors determined here point to the impact of S. aureus SCVs on chronic and persistent infections in advanced CF lung disease.