T
Thomas D. Schmittgen
Researcher at University of Florida
Publications - 119
Citations - 177830
Thomas D. Schmittgen is an academic researcher from University of Florida. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 48, co-authored 111 publications receiving 150512 citations. Previous affiliations of Thomas D. Schmittgen include University of Southern California & University of Oklahoma.
Papers
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Journal ArticleDOI
Enrichment of the erythrocyte miR-451a in brain extracellular vesicles following impairment of the blood-brain barrier.
Nasser Nassiri Koopaei,Ekram Ahmed Chowdhury,Jinmai Jiang,Behnam Noorani,Lais Da Silva,Gamze Bulut,Hesamedin Hakimjavadi,Srikar Chamala,Ulrich Bickel,Thomas D. Schmittgen +9 more
TL;DR: It is demonstrated that EVs containing miR-451a, a highly abundant miRNA present within erythrocytes and ery throat EVs, are enhanced in the CNS upon BBB disruption, suggesting that transfer of CNS EVs to the peripheral circulation did not occur under the conditions of the experiment.
Patent
Methods for quantifying microRNA precursors
TL;DR: In this paper, a method using gene-specific primers and reverse transcriptase to convert the primary miRNA precursors (pri-miRNA) and pre-miRNAs (pre-micoRNAs) to cDNA was presented.
Journal ArticleDOI
Method for improved integrity of RNA isolated from Matrigel cultures.
TL;DR: A simple method of removing Matrigel from primary cultures of human or mouse pancreatic acini is reported here and RNA isolated from the pelleted cells has high integrity and may be readily used for gene expression analysis such as quantitative reverse transcription PCR.
Journal ArticleDOI
Correction: Detection of microRNA Expression in Human Peripheral Blood Microvesicles
Melissa Piper Hunter,Noura Ismail,Xiaoli Zhang,Baltazar D. Aguda,Eun Joo Lee,Lianbo Yu,Tao Xiao,Jeffrey Schafer,Mei-Ling Ting Lee,Thomas D. Schmittgen,S. Patrick Nana-Sinkam,David Jarjoura,Clay B. Marsh +12 more
TL;DR: It is hypothesized that under normal healthy conditions, microvesicles contain miRNAs, contributing to biological homeostasis, and this study proves this hypothesis by characterization of circulating miRNA in healthy donors.