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Author

Thomas N. Thompson

Bio: Thomas N. Thompson is an academic researcher. The author has contributed to research in topics: Glass Vial & Energy source. The author has an hindex of 15, co-authored 18 publications receiving 1290 citations.

Papers
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Patent
18 Apr 1994
TL;DR: In this article, a syringe type apparatus which includes a unique fill assembly for use in controllably injecting medicinal fluids into a patient is described. But the filling assembly is not fully functional.
Abstract: This invention is a syringe type apparatus which includes a unique fill assembly (18) for use in controllably injecting medicinal fluids into a patient. The filling assembly (18) includes a pre-filled vial (24) which is partially received within a novel adapter assembly (26) that functions to operably couple the pre-filled vial (24) with the syringe assembly (16) of the apparatus. The body of the pre-filled vial (24) is surrounded by a protective covering until immediately prior to mating the assembly with the syringe assembly (16).

269 citations

Patent
17 Jan 1991
TL;DR: In this article, an apparatus for controllably intermixing two or more components in a sterile, closed environment to produce a flowable substance and then for expelling the flowable substances from the apparatus at a precisely controlled rate is presented.
Abstract: An apparatus for controllably intermixing two or more components in a sterile, closed environment to produce a flowable substance and then for expelling the flowable substance from the apparatus at a precisely controlled rate. The apparatus is particularly useful for medical applications and includes a dispenser portion with its own stored energy element provided in the form of an elastomeric membrane and a coupling mechanism for coupling a drug vial to the dispenser portion for controlled mixing a medicament contained within the drug vial with a diluent stored within the dispenser portion of the apparatus via a sterile pathway.

203 citations

Patent
23 Dec 1996
TL;DR: In this paper, a fluid delivery apparatus for continuous basal infusion, together with controlled bolus infusion of injectable medicaments, which embodies a stored energy source (66), such as distensible elastomeric membrane, which cooperates with a base and a conformable ullage to define a fluid reservoir.
Abstract: This invention is a fluid delivery apparatus for continuous basal infusion, together with controlled bolus infusion of injectable medicaments, which embodies a stored energy source (66), such as distensible elastomeric membrane, which cooperates with a base and a conformable ullage to define a fluid reservoir.

150 citations

Patent
10 Oct 2000
TL;DR: An implantable fluid delivery apparatus for infusing medicinal fluids into a patient that includes a novel basal delivery system that includes heat responsive polymer gel material which upon being heated by heater foil uniquely functions as an internal energy source for expelling basal doses of medicinal fluids from the device.
Abstract: An implantable fluid delivery apparatus for infusing medicinal fluids into a patient that includes a novel basal delivery system that includes a heat responsive polymer gel material which upon being heated by heater foil uniquely functions as an internal energy source for expelling basal doses of medicinal fluids from the device. The apparatus also includes a bolus delivery system that includes a magnetically responsive polymer gel which, upon being stimulated by an electro-magnet will delivery precise bolus doses of medicinal fluids to the patient.

99 citations

Patent
27 Aug 1998
TL;DR: In this paper, a thermal expanding polymer material is used as an internal energy source for expelling the medicinal fluids from the device, which can be used for subdermal, intradermal and intramuscular infusion of fluids.
Abstract: A fluid delivery apparatus (50) for infusing medicinal fluids into a patient which is of a compact, low profile, fluid storage device (52), laminate construction, with a cooperating and remotely located infusion means (54) for infusing the medicinal fluid (F) into the patient. The apparatus embodies a novel thermal expanding polymer material (70) which uniquely functions as an internal energy source for expelling the medicinal fluids from the device. The apparatus can be used for subdermal, intradermal and intramuscular infusion of fluids and in one form of the invention, includes a novel delivery cannula having a body portion disposed within a circuitous channel (108) formed within the base (56) of the apparatus and a pierceable portion (100d) which extends outwardly from the base of the apparatus.

90 citations


Cited by
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Patent
31 Aug 2001
TL;DR: In this article, the authors describe a system for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port and a local processor programmed to cause a flow of fluid to the exiting port based on flow instructions from a separate, remote control device.
Abstract: A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.

755 citations

Patent
02 Oct 2003
TL;DR: In this article, the authors proposed a method of delivering a liquid therapeutic agent to a patient using a drug delivery pump, which consists of an expandable and contractible enclosure having an interior volume that defines a medication reservoir; one or more electroactive polymer actuators; and a medication outlet port providing fluid communication between the interior volume of the contractible and expandable enclosure and an exterior of the delivery pump apparatus.
Abstract: The present invention is directed to a drug delivery pump apparatus, which comprises: (a) an expandable and contractible enclosure having an interior volume that defines a medication reservoir; (b) one or more electroactive polymer actuators; (c) a medication outlet port providing fluid communication between the interior volume of the contractible and expandable enclosure and an exterior of the delivery pump apparatus; and (d) a control unit electrically coupled to the one or more actuators and sending control signals to the same. The one or more electroactive polymer actuators act to reduce the interior volume of the contractible and expandable enclosure based upon the received control signals. The present invention is also directed to a method of delivering a liquid therapeutic agent to a patient. The method comprises: (a) providing the above infusion pump apparatus; (b) placing the outlet port of the infusion pump apparatus in fluid communication with a patient; and (c) sending the control signals to the one or more actuators to reduce the internal volume of the contractible and expandable enclosure, thereby forcing a portion of the liquid therapeutic agent within the medication reservoir through the outlet port and into the patient.

731 citations

Patent
22 Feb 2002
TL;DR: In this paper, a device for delivering fluid including a disposable assembly (800) having an exit port assembly (70) and a metering portion of a dispenser (40) for controlling fluid flow to the exit port assemblies (70), and a reusable assembly (700) having a control portion (46) of the dispenser(40) adapted to control the metering component of the dispenser (40), upon attachment of the reusable assembly(700) and the disposable assembly(800), a local processor (50) connected to the dispensers (40).
Abstract: A device (10) for delivering fluid including a disposable assembly (800) having an exit port assembly (70) and a metering portion of a dispenser (40) for controlling fluid flow to the exit port assembly (70), and a reusable assembly (700) having a control portion (46) of the dispenser (40) adapted to control the metering portion of the dispenser (40) upon attachment of the reusable assembly (700) and the disposable assembly (800), a local processor (50) connected to the dispenser (40) and programmed to cause fluid flow to the exit port assembly (70) through the dispenser (40) based upon flow instructions, and a local wireless communication element (60) connected to the local processor (50) for receiving flow instructions from a remote wireless device (100) The assemblies (700, 800) are adapted to be removably attached, and a power source (80) is contained in the disposable assembly (800) for providing power to the reusable assembly (700) upon attachment of the reusable assembly (700) and the disposable assembly (800)

676 citations

Patent
06 Dec 2005
TL;DR: In this article, the authors describe bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters.
Abstract: The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

551 citations

Patent
21 Dec 2001
TL;DR: In this paper, a system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device, is described, where information can be transferred between the local processor and the remote processor in a wireless manner.
Abstract: A system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device. The medical treatment apparatus has a local processor, and a local communication element connected to the local processor, while the remote control device includes a remote processor, user interface components connected to the remote processor, and a remote communication element connected to the remote processor and adapted to communicate with the local communication element of the medical treatment apparatus in a wireless manner such that information can be transferred between the local processor and the remote processor. The remote control device also includes at least two separate power supplies connected to the remote processor.

460 citations