T
Thomas P. Hopp
Researcher at New York Blood Center
Publications - 41
Citations - 10953
Thomas P. Hopp is an academic researcher from New York Blood Center. The author has contributed to research in topics: Peptide sequence & Amino acid. The author has an hindex of 27, co-authored 39 publications receiving 10759 citations. Previous affiliations of Thomas P. Hopp include Cornell University.
Papers
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Journal ArticleDOI
Prediction of protein antigenic determinants from amino acid sequences.
Thomas P. Hopp,Kenneth R. Woods +1 more
TL;DR: The method was developed using 12 proteins for which extensive immunochemical analysis has been carried out and subsequently was used to predict antigenic determinants for the following proteins, finding that the prediction success rate depended on averaging group length.
Journal ArticleDOI
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
Carl J. March,Bruce Mosley,Larsen Alf D,Douglas P. Cerretti,Gary Braedt,Virginia L. Price,Steven Gillis,Christopher S. Henney,Shirley R. Kronheim,Kenneth H. Grabstein,Paul J. Conlon,Thomas P. Hopp,David Cosman +12 more
TL;DR: Two distinct but distantly related complementary DNAs encoding proteins sharing human interleukin-1 (IL-1) activity (termed IL-lα and IL-1β), were isolated from a macrophage cDNA library.
Journal ArticleDOI
A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification.
Thomas P. Hopp,K S Prickett,Virginia L. Price,Randell T. Libby,Carl J. March,Douglas P. Cerretti,David L. Urdal,Paul J. Conlon +7 more
TL;DR: A small hydrophilic peptide of eight amino acids was engineered onto the N-terminus of a variety of recombinant lymphokines for the purpose of aiding in their detection and purification from yeast supernatants or E. coli extracts.
Patent
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
TL;DR: An immunoglobulin is defined as a mono-specific, hetero-molecular antibody which is monospecific to a single antigenic or allergenic determinant as mentioned in this paper.
Journal ArticleDOI
The cell surface receptors for interleukin-1α and interleukin-1β are identical
Steven K. Dower,Shirley R. Kronheim,Thomas P. Hopp,Michael A. Cantrell,Michael C Deeley,Steven Gillis,Christopher S. Henney,David L. Urdal +7 more
TL;DR: It is shown here that the receptor for IL-1α on both murine and human cells is identical to that forIL-1β, which raises the issue of what separation, if any, there might be between the biological activities of IL- 1α and IL-2β.