Thomas W. Panunto

Bio: Thomas W. Panunto is an academic researcher from University of Minnesota. The author has contributed to research in topics: Hydrogen bond & Molecule. The author has an hindex of 7, co-authored 10 publications receiving 940 citations.

1,3-Bis(m-nitrophenyl)urea: an exceptionally good complexing agent for proton acceptors

Abstract: Etude cristalline des composes d'addition obtenus avec le THF, la N,N-dimethyl p-nitroaniline, l'oxyde de triphenylphosphine et le diethyleneglycol

Solid-state and inclusion properties of hydrogen-bonded 1,3-cyclohexanedione cyclamers

Abstract: During crystallization 1,3-cyclohexanedione self assembles into either hydrogen-bonded chains or hexameric rings depending on the solvent conditions. The hexameric rings, called cyclamers, are the subject of this paper. These unusual structures occlude benzene as a guest molecule. The structural and crystal chemical properties of these host-guest compounds are explored here with the use of crystal growth studies, X-ray powder patterns, and thermal analysis. The crystal structure of the benzene cyclamer of 5-methyl-1,3-cyclohexanedione is reported (hexagonal,a =b = 19.19(2)A,c = 10.545(9)A,R3,Z = 18,V = 3362(6)A3; 717 unique reflections,R = 0.062). An analysis of the stereochemical implications of cyclic directionality in these cyclamers is also discussed.

The Halogen Bond

Abstract: The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.

Mechanochemistry: opportunities for new and cleaner synthesis

Abstract: The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal–organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).