Tiffany G. Baker

TL;DR: The data indicate that celastrol inhibits aminoglycoside ototoxicity via HSP32/HO-1 induction, and the major heat shock transcription factor HSF-1 is not required for Celastrol-mediated protection.

TL;DR: The data indicate that HSP induction protects against cisplatin-induced hair cell death, and they suggest that resident macrophages mediate the protective effect of HO-1 induction.

TL;DR: The data indicate that lovastatin reduces cisplatin-induced hearing loss in mice and suggest that concurrent statin and cisPlatin therapy may represent a feasible clinical strategy for reducing cisplin-induced ototoxicity that should be explored for future clinical use.

TL;DR: A rare case of an older patient with a large, petrous apex AFH that was clinically mistaken for a trigeminal nerve schwannoma is presented, and gross total resection of this lesion is preferable.

TL;DR: Large LOH driven by haploidization represents a defining molecular hallmark of a subtype of gcGBM and provides a diagnostic genomic hallmark to evaluate in future cases, may explain reported differences in survival, and suggests new therapeutic vulnerabilities.