T
Timir Tripathi
Researcher at North Eastern Hill University
Publications - 119
Citations - 2375
Timir Tripathi is an academic researcher from North Eastern Hill University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 21, co-authored 93 publications receiving 1442 citations. Previous affiliations of Timir Tripathi include Central Drug Research Institute.
Papers
More filters
Journal ArticleDOI
Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2.
TL;DR: A new, designed multi-peptide subunit-based epitope vaccine against COVID-19, made up of 33 highly antigenic epitopes from three proteins that have a prominent role in host-receptor recognition, viral entry, and pathogenicity is presented.
Journal ArticleDOI
One year update on the COVID-19 pandemic: Where are we now?
TL;DR: At the pandemic's 1-year mark, current information on SARS-CoV-2 origin and biology, and advances in the development of therapeutics are summarized.
Journal ArticleDOI
Current and novel therapeutic molecules and targets in Alzheimer's disease.
Ashwini Kumar,Chaluveelaveedu Murleedharan Nisha,Chitrangda Silakari,Isha Sharma,Kanukanti Anusha,Nityasha Gupta,Prateek Nair,Timir Tripathi,Awanish Kumar +8 more
TL;DR: The known drug targets of AD, in vivo active agents against AD, state-of-the-art docking studies done in AD, and future prospects of the docking with particular emphasis on AD are summarized.
Journal ArticleDOI
Aminoacyl-tRNA synthetases: Structure, function, and drug discovery
TL;DR: This review reviews the classification, function, and the conserved as well the appended structural architecture of these enzymes in detail, including its association with multi-synthetase complexes and their role in human diseases in terms of mutations and autoantibodies against AARSs.
Journal ArticleDOI
Molecular Docking and In Silico ADMET Study Reveals Acylguanidine 7a as a Potential Inhibitor of β-Secretase
Chaluveelaveedu Murleedharan Nisha,Ashwini Kumar,Prateek Nair,Nityasha Gupta,Chitrangda Silakari,Timir Tripathi,Awanish Kumar +6 more
TL;DR: Docking revealed that acylguanidine 7a has the lowest binding energy followed by MK-8931 and pioglitazone and binds significantly to β-secretase, and these compounds may serve as potential lead compound for developing new anti-Alzheimer drug.