T
Timothy E. Schlub
Researcher at University of Sydney
Publications - 95
Citations - 5834
Timothy E. Schlub is an academic researcher from University of Sydney. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 24, co-authored 75 publications receiving 2470 citations. Previous affiliations of Timothy E. Schlub include University of New South Wales.
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Journal ArticleDOI
Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.
David S. Khoury,Deborah Cromer,Arnold Reynaldi,Timothy E. Schlub,Timothy E. Schlub,Adam K. Wheatley,Jennifer A Juno,Kanta Subbarao,Stephen J. Kent,Stephen J. Kent,Stephen J. Kent,James A. Triccas,Miles P. Davenport +12 more
TL;DR: It is shown that neutralization level is highly predictive of immune protection, and an evidence-based model of SARS-CoV-2 immune protection that will assist in developing vaccine strategies to control the future trajectory of the pandemic is provided.
Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis.
Deborah Cromer,Megan Steain,Arnold Reynaldi,Timothy E. Schlub,Timothy E. Schlub,Adam K. Wheatley,Jennifer A Juno,Stephen J. Kent,Stephen J. Kent,James A. Triccas,David S. Khoury,Miles P. Davenport +11 more
TL;DR: In this paper, the authors explored whether in-vitro neutralization titres remain predictive of vaccine protection from infection with SARS-CoV-2 variants and used the model to predict the impact of booster vaccination on protection against SARS CoV2 variants.
Journal ArticleDOI
Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants
Bonnie Hiener,Bethany A Horsburgh,John-Sebastian Eden,Kirston Barton,Timothy E. Schlub,Eunok Lee,Susanne von Stockenstrom,Lina Odevall,Jeffrey M. Milush,Teri Liegler,Elizabeth Sinclair,Rebecca Hoh,Eli Boritz,Daniel C. Douek,Rémi Fromentin,Nicolas Chomont,Steven G. Deeks,Frederick Hecht,Sarah Palmer +18 more
TL;DR: The FLIPS assay identified multiple identical intact proviruses, suggesting a role for cellular proliferation in the maintenance of the latent HIV-1 reservoir and addressing the limitations of other methods that also genetically characterize the latent reservoir.
Journal ArticleDOI
Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19.
Adam K. Wheatley,Jennifer A Juno,Jing J. Wang,Kevin J. Selva,Arnold Reynaldi,Hyon-Xhi Tan,Wen Shi Lee,Kathleen M. Wragg,Hannah G. Kelly,Hannah G. Kelly,Robyn Esterbauer,Robyn Esterbauer,Samantha K Davis,Helen E Kent,Helen E Kent,Francesca L Mordant,Timothy E. Schlub,Timothy E. Schlub,David L. Gordon,David S. Khoury,Kanta Subbarao,Deborah Cromer,Tom P. Gordon,Tom P. Gordon,Amy W. Chung,Miles P. Davenport,Stephen J. Kent,Stephen J. Kent,Stephen J. Kent +28 more
TL;DR: In this paper, the authors show a comprehensive profile of antibody, B cell and T cell dynamics over time in a cohort of patients who have recovered from mild-moderate COVID-19.
Journal ArticleDOI
Low levels of SIV infection in sooty mangabey central memory CD4 + T cells are associated with limited CCR5 expression
Mirko Paiardini,Barbara Cervasi,Barbara Cervasi,Elane Reyes-Aviles,Luca Micci,Luca Micci,Alexandra M. Ortiz,Alexandra M. Ortiz,Ann Chahroudi,Carol L. Vinton,Shari N. Gordon,Shari N. Gordon,Steven E. Bosinger,Nicholas Francella,Paul L Hallberg,Elizabeth M. Cramer,Timothy E. Schlub,Ming Liang Chan,Nadeene E. Riddick,Ronald G. Collman,Cristian Apetrei,Ivona Pandrea,James G. Else,Jan Münch,Frank Kirchhoff,Miles P. Davenport,Jason M. Brenchley,Guido Silvestri,Guido Silvestri +28 more
TL;DR: It is found that, after in vitro stimulation, sooty mangabey CD4+ T cells fail to upregulate CCR5 and that this phenomenon is more pronounced inCD4+ central memory T cells (TCM cells).