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Timothy J. Onofrychuk
Researcher at University of Saskatchewan
Publications - 7
Citations - 28
Timothy J. Onofrychuk is an academic researcher from University of Saskatchewan. The author has contributed to research in topics: Cannabis & Medicine. The author has an hindex of 2, co-authored 4 publications receiving 8 citations.
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Journal ArticleDOI
Dissociable changes in spike and wave discharges following exposure to injected cannabinoids and smoked cannabis in Genetic Absence Epilepsy Rats from Strasbourg.
Andrew J. Roebuck,Andrew J. Roebuck,Quentin Greba,Timothy J. Onofrychuk,Dan L. McElroy,Thaísa M. Sandini,Ayat Zagzoog,Jonathan J. Simone,Stuart M. Cain,Terrance P. Snutch,Robert B. Laprairie,Robert B. Laprairie,John G. Howland +12 more
TL;DR: In this article, the effects of Δ9 -tetrahydrocannabinol (THC) and cannabidiol (CBD) exposure to smoke from two different chemovars of cannabis were tested in GAERS.
Journal ArticleDOI
Effects of the cannabinoid receptor 1 positive allosteric modulator GAT211 and acute MK-801 on visual attention and impulsivity in rats assessed using the five-choice serial reaction time task
Timothy J. Onofrychuk,Shuang Cai,Dan L. McElroy,Andrew J. Roebuck,Quentin Greba,Sumanta Garai,Ganesh A. Thakur,Robert B. Laprairie,John G. Howland +8 more
TL;DR: The dramatic effects of acute MK-801 treatment on behavioral measures of attention and impulsivity are confirmed and continued investigation of CB1R positive allosteric modulators as potential treatments for the cognitive symptoms of schizophrenia and related disorders should be pursued.
Journal ArticleDOI
The effects of acute Cannabis smoke or Δ9-THC injections on the trial-unique, nonmatching-to-location and five-choice serial reaction time tasks in male Long-Evans rats
Ilne L. Barnard,Timothy J. Onofrychuk,Thaísa Meira Sandini,Dan L. McElroy,Ayat Zagzoog,Andrew J. Roebuck,Faith V. Austin-Scott,Robert B. Laprairie,John G. Howland +8 more
TL;DR: In this article , the effects of acute smoke exposure, nor injected THC, impacted attentional processes, impulsivity, perseverations, or response latencies in the 5-CSRTT.
Journal ArticleDOI
Implementation of ezTrack open-source pipeline for quantifying rat locomotor behavior: Comparison to commercially available software.
Dan L. McElroy,Andrew J. Roebuck,Timothy J. Onofrychuk,Thaísa M. Sandini,Quentin Greba,John G. Howland +5 more
TL;DR: A free open-source behavioral tracking pipeline called ezTrack was compared to commercially available software for assessing rat locomotor behavior and time spent in regions of interest during elevated plus maze (EPM) and open field test (OFT) assays and suggest that ez track is a cost-effective approach to quantify some aspects of behavior in these tasks.
Journal ArticleDOI
The Touchscreen-Based Trial-Unique, Nonmatching-To-Location (TUNL) Task as a Measure of Working Memory and Pattern Separation in Rats and Mice
TL;DR: The TUNL task as mentioned in this paper is an automated touchscreen task used to evaluate the cognitive processes involved in working memory (WM) and spatial pattern separation in rodents, which is used to assess working memory and cognitive deficits in rodent models with neurodegenerative and neurological disorders, providing a valuable tool to screen for new treatment options, in addition to assessing basic neurobiology.