T
Tin Oo Khor
Researcher at Rutgers University
Publications - 69
Citations - 7518
Tin Oo Khor is an academic researcher from Rutgers University. The author has contributed to research in topics: Tramp & Carcinogenesis. The author has an hindex of 46, co-authored 69 publications receiving 6793 citations.
Papers
More filters
Journal ArticleDOI
Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis
TL;DR: In vivo and in vitro data generated from the laboratory suggest that many dietary compounds can differentially regulate Nrf2-mediated antioxidant/anti-inflammatory signaling pathways as the first line defense or induce apoptosis once the cells have been damaged.
Journal ArticleDOI
Nrf2-Deficient Mice Have an Increased Susceptibility to Dextran Sulfate Sodium–Induced Colitis
TL;DR: The data suggests that Nrf2 could play an important role in protecting intestinal integrity, through regulation of proinflammatory cytokines and induction of phase II detoxifying enzymes.
Journal ArticleDOI
Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability.
TL;DR: This review summarizes the latest research in cancer chemoprevention and treatment using the bioactive components from natural plants and relevant molecular mechanisms involved in the pharmacological effects of these phytochemicals are discussed.
Journal ArticleDOI
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.
Changjiang Xu,Mou-Tuan Huang,Guoxiang Shen,Xiaoling Yuan,Wen Lin,Tin Oo Khor,Allan H. Conney,Ah-Ng Tony Kong +7 more
TL;DR: The results show for the first time that Nrf2(-/-) mice are more susceptible to skin tumorigenesis and that the chemopreventive effects of sulforaphane are mediated, at least in part, through NRF2.
Journal ArticleDOI
Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer
Tin Oo Khor,Mou-Tuan Huang,Auemduan Prawan,Yue Liu,Xingpei Hao,Siwang Yu,William Cheung,Jefferson Y. Chan,Bandaru S. Reddy,Chung S. Yang,Ah-Ng Tony Kong +10 more
TL;DR: The findings show that Nrf2 plays a critical role in protecting against inflammation-associated colorectal cancer.