T
Tiziana Bachetti
Researcher at Istituto Giannina Gaslini
Publications - 42
Citations - 2970
Tiziana Bachetti is an academic researcher from Istituto Giannina Gaslini. The author has contributed to research in topics: Nitric oxide synthase & Nitric oxide. The author has an hindex of 23, co-authored 42 publications receiving 2855 citations. Previous affiliations of Tiziana Bachetti include University of Brescia.
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Journal ArticleDOI
Tumor Necrosis Factor Soluble Receptors in Patients With Various Degrees of Congestive Heart Failure
Roberto Ferrari,Tiziana Bachetti,Roberta Confortini,Cristina Opasich,Oreste Febo,Angelo Corti,Giovanni Cassani,Odoardo Visioli +7 more
TL;DR: Measurement of sTNF-Rs, in addition to antigenic and bioactive TNF-alpha, is essential for evaluation of the activation of this cytokine in CHF and might inhibit the in vitro cytotoxicity of T NF-alpha.
Journal Article
Oxidative stress during myocardial ischaemia and heart failure
Roberto Ferrari,Laura Agnoletti,Laura Comini,G. Gaia,Tiziana Bachetti,Anna Cargnoni,Claudio Ceconi,Salvatore Curello,Odoardo Visioli +8 more
TL;DR: In this paper, the authors showed that the immunological response to heart failure may result in endothelial and myocyte dysfunction through oxidative stress-mediated apoptosis, where tumour necrosis factor causes a rapid rise in intracellular reactive oxygen intermediates and apoptosis.
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Serum From Patients With Severe Heart Failure Downregulates eNOS and Is Proapoptotic Role of Tumor Necrosis Factor-α
Laura Agnoletti,Salvatore Curello,Tiziana Bachetti,Fabio Malacarne,G. Gaia,Laura Comini,Maurizio Volterrani,Paolo Bonetti,Giovanni Parrinello,Moris Cadei,Pier Giovanni Grigolato,Roberto Ferrari +11 more
TL;DR: Serum from patients with severe CHF downregulates eNOS expression and increases apoptosis, and high levels of TNF-alpha likely play a role, but they cannot be the only factor responsible.
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Circulating levels of tumour necrosis factor-α and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
M. Poloni,Dante Facchetti,Roberto Mai,A. Micheli,Laura Agnoletti,Gloria Francolini,Gabriele Mora,Camana C,Letizia Mazzini,Tiziana Bachetti +9 more
TL;DR: An activation of the TNF system in ALS is reported and the role of this activation in the pathogenesis of the disease remains elusive.
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Chromogranin A in heart failure; a novel neurohumoral factor and a predictor for mortality.
Claudio Ceconi,Roberto Ferrari,Tiziana Bachetti,Cristina Opasich,Maurizio Volterrani,Barbara Colombo,G. Parrinello,Angelo Corti +7 more
TL;DR: CgA serum levels are increased in patients with chronic heart failure and are a predictive factor for mortality, and is a pro-hormone, precursor of several active fragments likely to exert biological effects in Chronic heart failure.