T
Tobias Bleicker
Researcher at Humboldt University of Berlin
Publications - 20
Citations - 14477
Tobias Bleicker is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Viral load & Biology. The author has an hindex of 14, co-authored 16 publications receiving 10496 citations. Previous affiliations of Tobias Bleicker include Charité & University of Bonn.
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Journal ArticleDOI
Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR.
Victor M. Corman,Olfert Landt,Marco Kaiser,Richard Molenkamp,Adam Meijer,Daniel K.W. Chu,Tobias Bleicker,Sebastian Brünink,Julia Schneider,Marie Luisa Schmidt,Daphne G.J.C. Mulders,Bart L. Haagmans,Bas van der Veer,Sharon van den Brink,Lisa Wijsman,Gabriel Goderski,Jean Louis Romette,Joanna Ellis,Maria Zambon,Malik Peiris,Herman Goossens,Chantal B.E.M. Reusken,Marion Koopmans,Christian Drosten +23 more
TL;DR: A validated diagnostic workflow for 2019-nCoV is presented, its design relying on close genetic relatedness of 2019- nCoV with SARS coronavirus, making use of synthetic nucleic acid technology.
Journal ArticleDOI
Virological assessment of hospitalized patients with COVID-2019.
Roman Wölfel,Victor M. Corman,Wolfgang Guggemos,M Seilmaier,Sabine Zange,Marcel A. Müller,Daniela Niemeyer,Terry Jones,Terry Jones,Patrick Vollmar,Camilla Rothe,Michael Hoelscher,Tobias Bleicker,Sebastian Brünink,Julia Schneider,Rosina Ehmann,Katrin Zwirglmaier,Christian Drosten,Clemens M. Wendtner +18 more
TL;DR: Detailed virological analysis of nine cases of coronavirus disease 2019 (COVID-19) provides proof of active replication of the SARS-CoV-2 virus in tissues of the upper respiratory tract.
Journal ArticleDOI
Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction
Victor M. Corman,Isabella Eckerle,Tobias Bleicker,Ali Moh Zaki,Olfert Landt,Monika Eschbach-Bludau,S. van Boheemen,Robin Gopal,M Ballhause,Theo M. Bestebroer,Doreen Muth,Marcel A. Müller,Jan Felix Drexler,Maria Zambon,A.D.M.E. Osterhaus,R M Fouchier,Christian Drosten +16 more
TL;DR: Two real-time reverse-transcription polymerase chain reaction assays for a novel human coronavirus, targeting regions upstream of the E gene (upE) or within open reading frame (ORF)1b, respectively, observed no cross-reactivity with coronaviruses OC43, NL63, 229E, SARS-CoV or with 92 clinical specimens containing common human respiratory viruses.
Posted ContentDOI
Clinical presentation and virological assessment of hospitalized cases of coronavirus disease 2019 in a travel-associated transmission cluster
Roman Woelfel,Victor M. Corman,Wolfgang Guggemos,M Seilmaier,Sabine Zange,Marcel A Mueller,Daniela Niemeyer,Patrick Vollmar,Camilla Rothe,Michael Hoelscher,Tobias Bleicker,Bruenink S,Julia Schneider,Rosina Ehmann,Katrin Zwirglmaier,Christian Drosten,Clemens M. Wendtner +16 more
TL;DR: It is shown that COVID-19 can often present as a common cold-like illness, and SARS-CoV-2 can actively replicate in the upper respiratory tract, and is shed for a prolonged time after symptoms end, including in stool.
Journal ArticleDOI
Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections.
Victor M. Corman,Marcel A. Müller,Ulrich Costabel,Jörg Timm,Tabea Binger,Bernhard Meyer,Petra Kreher,Erik Lattwein,Monika Eschbach-Bludau,Andreas Nitsche,Tobias Bleicker,Olfert Landt,Brunhilde Schweiger,Jan Felix Drexler,Albert D. M. E. Osterhaus,Bart L. Haagmans,Ulf Dittmer,F. Bonin,Thorsten Wolff,Christian Drosten +19 more
TL;DR: A rigorously validated and highly sensitive confirmatory real-time RT-PCR assay (1A assay) that can be used in combination with the previously reported upE assay is presented.