Tobias Paczian

TL;DR: A fully automated service for annotating bacterial and archaeal genomes that identifies protein-encoding, rRNA and tRNA genes, assigns functions to the genes, predicts which subsystems are represented in the genome, uses this information to reconstruct the metabolic network and makes the output easily downloadable for the user.

TL;DR: The open-source metagenomics RAST service provides a new paradigm for the annotation and analysis of metagenomes that is stable, extensible, and freely available to all researchers.

TL;DR: This work presents several examples integrating data and analyses from MG-RAST into popular third-party analysis tools or sequence alignment tools, and reports changes to the analysis workflow and the technologies used to scale the pipeline up to the required throughput levels.

TL;DR: The National Microbial Pathogen Data Resource (NMPDR) contains the complete genomes of ∼50 strains of pathogenic bacteria that are the focus of the curators, as well as >400 other genomes that provide a broad context for comparative analysis across the three phylogenetic Domains.

TL;DR: The MG-RAST team intends to support the Common Workflow Language as a standard to specify bioinformatics workflows, both to facilitate development and efficient high-performance implementation of the community's data analysis tasks.