T
Todd K. Jones
Researcher at Merck & Co.
Publications - 43
Citations - 1882
Todd K. Jones is an academic researcher from Merck & Co.. The author has contributed to research in topics: Enantioselective synthesis & Total synthesis. The author has an hindex of 17, co-authored 43 publications receiving 1854 citations. Previous affiliations of Todd K. Jones include University of Illinois at Urbana–Champaign & Harvard University.
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Total synthesis of the macrolide antibiotic cytovaricin
TL;DR: A convergent asymmetric synthesis of the antinoeplastic macrolide antibiotic cytovaricin has been achieved through the synthesis and coupling of the illustrated spiroketal and polyol glycoside subunits.
Journal ArticleDOI
A practical enantioselective synthesis of .alpha.,.alpha.-diaryl-2-pyrrolidinemethanol. Preparation and chemistry of the corresponding oxazaborolidines
David J. Mathre,Todd K. Jones,Lyndon C. Xavier,Thomas J. Blacklock,Robert A. Reamer,Julie J. Mohan,E. Tracy Turner Jones,Karst Hoogsteen,Mary W. Baum,Edward J. J. Grabowski +9 more
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Chemistry of tricarbonyl hemiketals and application of Evans technology to the total synthesis of the immunosuppressant (-)-FK-506
TL;DR: In this paper, the chemistry of the tricarbonyl region of FK-506 and its use in designing a sucessful route to this immunosuppressant is outlined.