scispace - formally typeset
Search or ask a question
Author

Tom J. Mabry

Bio: Tom J. Mabry is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Kaempferol & Sesquiterpene lactone. The author has an hindex of 42, co-authored 459 publications receiving 13375 citations. Previous affiliations of Tom J. Mabry include University of Illinois at Urbana–Champaign & Minia University.


Papers
More filters
Journal ArticleDOI
TL;DR: Distributional data for 12 flavonoids in 23 taxa of Oenothera, 2 species of Calylophus, and 1 species of Gaura are presented.

34 citations

Journal ArticleDOI
TL;DR: In this paper, 6,8-Dihydroxykaempferol 3-rutinoside, along with quercetin and its 3- O -rutino-7-glucoside, were isolated from the leaves of Withania somnifera.

33 citations

Journal ArticleDOI
TL;DR: Betalamic acid, the probable key intermediate in the biogenesis of all betalains, has been detected for the first time as a natural product in numerous species of plants belonging to families of the Order Centrospermae.
Abstract: Betalamic acid, the probable key intermediate in the biogenesis of all betalains, has been detected for the first time as a natural product in numerous species of plants belonging to families of the Order Centrospermae, has been obtained directly from the cleavage of the red beet pigment betanin, and has been characterized by the formation of betanidin when mixed with synthetic cyclodopa, and indicaxanthin on reaction with L-proline.

33 citations

Journal ArticleDOI
TL;DR: The structure and stereochemistry of tamaulipin-A (Ia), a new germacranolide isolated from Ambrosia confertiflora, was determined in part by conversion to a product also derived from saussurea lactone, a sesquiterpene lactone of known absolute structure as mentioned in this paper.

33 citations

Journal ArticleDOI
TL;DR: Three new and eight known flavonols, all containing 6-methoxyl groups, were isolated from Brickellia veronicaefolia as discussed by the authors, and the new compounds were eupatolitin 3-sulfate, 6methoxyquercetin 7,3′-dimethyl ether (veronicafolin) 3-digalactoside and veronicafolis 3-Sulfate.

32 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase.

8,513 citations

Journal ArticleDOI
TL;DR: A revised and updated classification for the families of the flowering plants is provided in this paper, which includes Austrobaileyales, Canellales, Gunnerales, Crossosomatales and Celastrales.

7,299 citations

Journal Article
TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
Abstract: Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea, and red wine. They are low molecular weight compounds composed of a three-ring structure with various substitutions. This basic structure is shared by tocopherols (vitamin E). Flavonoids can be subdivided according to the presence of an oxy group at position 4, a double bond between carbon atoms 2 and 3, or a hydroxyl group in position 3 of the C (middle) ring. These characteristics appear to also be required for best activity, especially antioxidant and antiproliferative, in the systems studied. The particular hydroxylation pattern of the B ring of the flavonoles increases their activities, especially in inhibition of mast cell secretion. Certain plants and spices containing flavonoids have been used for thousands of years in traditional Eastern medicine. In spite of the voluminous literature available, however, Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional. Suggestions are made where such possibilities may be worth pursuing.

4,663 citations

Journal ArticleDOI
TL;DR: In this article, two complementary colorimetric methods, aluminum chloride method and 2,4-dini trophenylhydrazine method, were used to determine the real content of total flavonoids in propolis.

3,899 citations

Journal ArticleDOI
TL;DR: Several high-quality investigations have examined the relationship between flavonoid structure and antibacterial activity and these are in close agreement, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.

3,630 citations