Author
Tom J. Mabry
Other affiliations: University of Illinois at Urbana–Champaign, Minia University, Dicle University ...read more
Bio: Tom J. Mabry is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Kaempferol & Sesquiterpene lactone. The author has an hindex of 42, co-authored 459 publications receiving 13375 citations. Previous affiliations of Tom J. Mabry include University of Illinois at Urbana–Champaign & Minia University.
Topics: Kaempferol, Sesquiterpene lactone, Germacranolide, Flavones, Hymenoxys
Papers published on a yearly basis
Papers
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TL;DR: NMR, UV, and MS spectral data confirm the structure of calycopterin as 5,4′-dihydroxy-3,6,7,8-tetramethoxyflavone.
21 citations
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TL;DR: The structure of the new compound was determined by spectroscopic methods including an attached proton test experiment and CI mass spectrometry as 6,7-dimethoxy-3,5,3′,4′-tetrahydroxyflavone 3-O -apioside as discussed by the authors.
21 citations
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TL;DR: The whole plant flavonoid chemistry was strikingly different from that found previously in chitin-treated cell suspension cultures of the same plant.
21 citations
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TL;DR: The structure assigned to artemisiifolin was previously ascribed to a salonitenolide, a germacranolide from Centaurea saloitana Vis, but preliminary studies suggest that the structure of salonitanolide should be revised to formula II.
21 citations
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TL;DR: A new highly oxygenated flavone methyl ether has been isolated from Brickellia veronicaefolia and B. chlorolepis as mentioned in this paper, which was identified as 5,6′-dihydroxy-6,7,2′,3′,4′-pentamethoxyflavone and given the name brickellin.
21 citations
Cited by
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TL;DR: The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase.
8,513 citations
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TL;DR: A revised and updated classification for the families of the flowering plants is provided in this paper, which includes Austrobaileyales, Canellales, Gunnerales, Crossosomatales and Celastrales.
7,299 citations
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TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
Abstract: Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea, and red wine. They are low molecular weight compounds composed of a three-ring structure with various substitutions. This basic structure is shared by tocopherols (vitamin E). Flavonoids can be subdivided according to the presence of an oxy group at position 4, a double bond between carbon atoms 2 and 3, or a hydroxyl group in position 3 of the C (middle) ring. These characteristics appear to also be required for best activity, especially antioxidant and antiproliferative, in the systems studied. The particular hydroxylation pattern of the B ring of the flavonoles increases their activities, especially in inhibition of mast cell secretion. Certain plants and spices containing flavonoids have been used for thousands of years in traditional Eastern medicine. In spite of the voluminous literature available, however, Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional. Suggestions are made where such possibilities may be worth pursuing.
4,663 citations
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TL;DR: In this article, two complementary colorimetric methods, aluminum chloride method and 2,4-dini trophenylhydrazine method, were used to determine the real content of total flavonoids in propolis.
3,899 citations
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TL;DR: Several high-quality investigations have examined the relationship between flavonoid structure and antibacterial activity and these are in close agreement, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.
3,630 citations