Author
Tom J. Mabry
Other affiliations: University of Illinois at Urbana–Champaign, Minia University, Dicle University ...read more
Bio: Tom J. Mabry is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Kaempferol & Sesquiterpene lactone. The author has an hindex of 42, co-authored 459 publications receiving 13375 citations. Previous affiliations of Tom J. Mabry include University of Illinois at Urbana–Champaign & Minia University.
Topics: Kaempferol, Sesquiterpene lactone, Germacranolide, Flavones, Hymenoxys
Papers published on a yearly basis
Papers
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TL;DR: Three new heliangolides (niveusin-A, -B and -C) were isolated and characterized from a CHCl 3 extract of Helianthus niveus and the structures were deduced by 1 H and 13 C NMR as well as extensive decoupling experiments and derivatizations.
59 citations
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TL;DR: Two new and eleven known 6-methoxyflavonoids were identified in leaf tissue of Brickellia californica as mentioned in this paper, including eupatin 3-SO3 Ca1/2 and patuletin 3 -SO3K.
58 citations
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TL;DR: In this paper, the presence of hydroxyl or methoxyl groups at C 6 in flavones and 3-substituted flavonols is indicated when, in the UV spectral analysis in MeOH with added AlCl 3 -HCl, a Band I bathochomic shift (relative to the MeOH spectrum) of about 20 nm is observed for the C 5 -hydroxy-C 4 -keto-AlCl 3 complex; the procedure distinguishes C 6 oxygenation from that at C 8 in these compounds.
58 citations
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TL;DR: The structures of two new germacranolides, glaucolide-A ( 1a ) and -B ( 1b ), isolated from more than 25 species of Vernonia from the Western Hemisphere, have been established by a series of chemical transformations, and spectral and X-ray crystallographic studies as discussed by the authors.
56 citations
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TL;DR: Systematic and evolutionary interpretations based upon the distributional data for 27 flavonoids from 39 species and 9 sesquiterpene lactones from 38 species are presented for species of Vernonia mostly from the New World.
56 citations
Cited by
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TL;DR: The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase.
8,513 citations
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TL;DR: A revised and updated classification for the families of the flowering plants is provided in this paper, which includes Austrobaileyales, Canellales, Gunnerales, Crossosomatales and Celastrales.
7,299 citations
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TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
Abstract: Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea, and red wine. They are low molecular weight compounds composed of a three-ring structure with various substitutions. This basic structure is shared by tocopherols (vitamin E). Flavonoids can be subdivided according to the presence of an oxy group at position 4, a double bond between carbon atoms 2 and 3, or a hydroxyl group in position 3 of the C (middle) ring. These characteristics appear to also be required for best activity, especially antioxidant and antiproliferative, in the systems studied. The particular hydroxylation pattern of the B ring of the flavonoles increases their activities, especially in inhibition of mast cell secretion. Certain plants and spices containing flavonoids have been used for thousands of years in traditional Eastern medicine. In spite of the voluminous literature available, however, Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional. Suggestions are made where such possibilities may be worth pursuing.
4,663 citations
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TL;DR: In this article, two complementary colorimetric methods, aluminum chloride method and 2,4-dini trophenylhydrazine method, were used to determine the real content of total flavonoids in propolis.
3,899 citations
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TL;DR: Several high-quality investigations have examined the relationship between flavonoid structure and antibacterial activity and these are in close agreement, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.
3,630 citations