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Tom J. Mabry

Bio: Tom J. Mabry is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Kaempferol & Sesquiterpene lactone. The author has an hindex of 42, co-authored 459 publications receiving 13375 citations. Previous affiliations of Tom J. Mabry include University of Illinois at Urbana–Champaign & Minia University.


Papers
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TL;DR: In this paper, cassumunarins A, B, and C were isolated from the rhizomes of Zingiber cassumum and the structures were determined by spectroscopic methods to be complex curcuminoids.
Abstract: New antioxidants, cassumunarins A, B, and C, were isolated from the rhizomes ofZingiber cassumunar, and the structures were determined by spectroscopic methods to be complex curcuminoids. The antixidant efficiency of cassumunarins was determined by inhibitory activity of autoxidation of linoleic acid in a buffer-ethanol system. The anti-inflammatory effect was measured by inhibition of edema formation on mouse ear induced by 12-O-tetradecanoylphorbol-13-acetate. Both types of activities were stronger for the cassumunarins than for the curcumin.

55 citations

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TL;DR: Larvae feeding on sunflower inflorescences in laboratory and greenhouse bioassays performed significantly poorer on 14 Helianthus species than on the cultivar hybrid ‘894’, and the sesquiterpene lactone 8 β-sarracinoyloxycumambranolide isolated from glandular trichomes on anthers ofHelianthus maximiliani Schrader was toxic to young larvae in bioassay.
Abstract: Sunflower moth, Homoeosoma electellum (Hulst), is a major pest of cultivated sunflower, Helianthus annuus L., in North America. Thirty perennial and 11 annual species of Helianthus and several cultivars of sunflower were evaluated for resistance to H. electellum larvae. Larvae feeding on sunflower inflorescences in laboratory and greenhouse bioassays performed significantly poorer on 14 Helianthus species than on the cultivar hybrid ‘894’. In in vitro bioassays, nonpolar extracts from H. annuus, Helianthus argophyllus Torrey & Gray, Helianthus ciliaris DC, and Helianthus petiolaris ssp. petiolaris Nuttall caused significant lengthening of larval stadia and retarded larval growth. Larvae feeding on purified sesquiterpene lactones and diterpenes from H. argophyllus , H. ciliaris, Helianthus angustifolius L., and Helianthus mollis Lambert in a wheat-germ diet at 0.1–1.0% concentration experienced high mortality, retarded growth, and an extended developmental period. The sesquiterpene lactone 8 β-sarracinoyloxycumambranolide isolated from glandular trichomes on anthers of Helianthus maximiliani Schrader was toxic to young larvae in bioassays. Two mechanisms giving Helianthus resistance to seed injury by larvae of H. electellum are terpenes in the florets and phytomelanin in the pericarp of seeds.

52 citations

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TL;DR: In this article, 14 daucane esters together with a known propiophenone 3,4-methylenedioxy-5-hydroxy-propiophenone were isolated from Ferula communis subsp. communis.

51 citations

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TL;DR: In this article, Kaur-16-en-19-oic acid and tetrachyrin, a rearranged kaurenoid lactone, were isolated from Tetrachyron orizabaensis var. websteri and Helianthus debilis ssp.debilis.

50 citations


Cited by
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TL;DR: The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase.

8,513 citations

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TL;DR: A revised and updated classification for the families of the flowering plants is provided in this paper, which includes Austrobaileyales, Canellales, Gunnerales, Crossosomatales and Celastrales.

7,299 citations

Journal Article
TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
Abstract: Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea, and red wine. They are low molecular weight compounds composed of a three-ring structure with various substitutions. This basic structure is shared by tocopherols (vitamin E). Flavonoids can be subdivided according to the presence of an oxy group at position 4, a double bond between carbon atoms 2 and 3, or a hydroxyl group in position 3 of the C (middle) ring. These characteristics appear to also be required for best activity, especially antioxidant and antiproliferative, in the systems studied. The particular hydroxylation pattern of the B ring of the flavonoles increases their activities, especially in inhibition of mast cell secretion. Certain plants and spices containing flavonoids have been used for thousands of years in traditional Eastern medicine. In spite of the voluminous literature available, however, Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional. Suggestions are made where such possibilities may be worth pursuing.

4,663 citations

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TL;DR: In this article, two complementary colorimetric methods, aluminum chloride method and 2,4-dini trophenylhydrazine method, were used to determine the real content of total flavonoids in propolis.

3,899 citations

Journal ArticleDOI
TL;DR: Several high-quality investigations have examined the relationship between flavonoid structure and antibacterial activity and these are in close agreement, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.

3,630 citations