Tom L. Blundell

TL;DR: A comparative protein modelling method designed to find the most probable structure for a sequence given its alignment with related structures, which is automated and illustrated by the modelling of trypsin from two other serine proteinases.

TL;DR: A novel approach (pkCSM) which uses graph-based signatures to develop predictive models of central ADMET properties for drug development and performs as well or better than current methods.

TL;DR: It is demonstrated that the combination of these three key features implemented in FUGUE improves both homology recognition performance and alignment accuracy.

TL;DR: The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments.

TL;DR: The physical, chemical, and biological properties of insulin in the light of the atomic arrangement found in insulin crystals are reviewed in this paper, where the relation of the three-dimensional arrangement of the atoms in the molecule of 2-zinc insulin crystal to the solution properties of the insulin (particularly its states of aggregation), to the chemical reaction and chemical modification of the molecule, and to its primary biological activity is discussed.