T
Tomislav Šmuc
Researcher at Laureate International Universities
Publications - 105
Citations - 7524
Tomislav Šmuc is an academic researcher from Laureate International Universities. The author has contributed to research in topics: Support vector machine & Cluster analysis. The author has an hindex of 23, co-authored 103 publications receiving 5909 citations.
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Journal ArticleDOI
REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
TL;DR: REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures.
Journal ArticleDOI
A large-scale evaluation of computational protein function prediction
Predrag Radivojac,Wyatt T. Clark,Tal Ronnen Oron,Alexandra M. Schnoes,Tobias Wittkop,Artem Sokolov,Artem Sokolov,Kiley Graim,Christopher S. Funk,Karin Verspoor,Asa Ben-Hur,Gaurav Pandey,Gaurav Pandey,Jeffrey M. Yunes,Ameet Talwalkar,Susanna Repo,Susanna Repo,Michael L Souza,Damiano Piovesan,Rita Casadio,Zheng Wang,Jianlin Cheng,Hai Fang,Julian Gough,Patrik Koskinen,Petri Törönen,Jussi Nokso-Koivisto,Liisa Holm,Domenico Cozzetto,Daniel W. A. Buchan,Kevin Bryson,David T. Jones,Bhakti Limaye,Harshal Inamdar,Avik Datta,Sunitha K Manjari,Rajendra Joshi,Meghana Chitale,Daisuke Kihara,Andreas Martin Lisewski,Serkan Erdin,Eric Venner,Olivier Lichtarge,Robert Rentzsch,Haixuan Yang,Alfonso E. Romero,Prajwal Bhat,Alberto Paccanaro,Tobias Hamp,Rebecca Kaßner,Stefan Seemayer,Esmeralda Vicedo,Christian Schaefer,Dominik Achten,Florian Auer,Ariane Boehm,Tatjana Braun,Maximilian Hecht,Mark Heron,Peter Hönigschmid,Thomas A. Hopf,Stefanie Kaufmann,Michael Kiening,Denis Krompass,Cedric Landerer,Yannick Mahlich,Manfred Roos,Jari Björne,Tapio Salakoski,Andrew Wong,Hagit Shatkay,Hagit Shatkay,Fanny Gatzmann,Ingolf Sommer,Mark N. Wass,Michael J.E. Sternberg,Nives Škunca,Fran Supek,Matko Bošnjak,Panče Panov,Sašo Džeroski,Tomislav Šmuc,Yiannis A. I. Kourmpetis,Yiannis A. I. Kourmpetis,Aalt D. J. van Dijk,Cajo J. F. ter Braak,Yuanpeng Zhou,Qingtian Gong,Xinran Dong,Weidong Tian,Marco Falda,Paolo Fontana,Enrico Lavezzo,Barbara Di Camillo,Stefano Toppo,Liang Lan,Nemanja Djuric,Yuhong Guo,Slobodan Vucetic,Amos Marc Bairoch,Amos Marc Bairoch,Michal Linial,Patricia C. Babbitt,Steven E. Brenner,Christine A. Orengo,Burkhard Rost,Sean D. Mooney,Iddo Friedberg +107 more
TL;DR: Today's best protein function prediction algorithms substantially outperform widely used first-generation methods, with large gains on all types of targets, and there is considerable need for improvement of currently available tools.
Journal ArticleDOI
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Naihui Zhou,Yuxiang Jiang,Timothy Bergquist,Alexandra J. Lee,Balint Z. Kacsoh,Alex W. Crocker,Kimberley A. Lewis,George Georghiou,Huy N Nguyen,Nafiz Hamid,Larry Davis,Tunca Doğan,Tunca Doğan,Volkan Atalay,Ahmet Sureyya Rifaioglu,Alperen Dalkiran,Rengul Cetin Atalay,Chengxin Zhang,Rebecca L. Hurto,Peter L. Freddolino,Yang Zhang,Prajwal Bhat,Fran Supek,José M. Fernández,Branislava Gemovic,Vladimir Perovic,Radoslav Davidovic,Neven Sumonja,Nevena Veljkovic,Ehsaneddin Asgari,Mohammad R. K. Mofrad,Giuseppe Profiti,Giuseppe Profiti,Castrense Savojardo,Pier Luigi Martelli,Rita Casadio,Florian Boecker,Heiko Schoof,Indika Kahanda,Natalie Thurlby,Alice C. McHardy,Alexandre Renaux,Alexandre Renaux,Rabie Saidi,Julian Gough,Alex A. Freitas,Magdalena Antczak,Fabio Fabris,Mark N. Wass,Jie Hou,Jianlin Cheng,Zheng Wang,Alfonso E. Romero,Alberto Paccanaro,Haixuan Yang,Haixuan Yang,Tatyana Goldberg,Chenguang Zhao,Liisa Holm,Petri Törönen,Alan Medlar,Elaine Zosa,Itamar Borukhov,Ilya Novikov,Angela D. Wilkins,Olivier Lichtarge,Po-Han Chi,Wei-Cheng Tseng,Michal Linial,Peter W. Rose,Christophe Dessimoz,Christophe Dessimoz,Christophe Dessimoz,Vedrana Vidulin,Saso Dzeroski,Ian Sillitoe,Sayoni Das,Jonathan G. Lees,Jonathan G. Lees,David T. Jones,David T. Jones,Cen Wan,Cen Wan,Domenico Cozzetto,Domenico Cozzetto,Rui Fa,Rui Fa,Mateo Torres,Alex Warwick Vesztrocy,Alex Warwick Vesztrocy,Jose Manuel Rodriguez,Michael L. Tress,Marco Frasca,Marco Notaro,Giuliano Grossi,Alessandro Petrini,Matteo Re,Giorgio Valentini,Marco Mesiti,Marco Mesiti,Daniel B. Roche,Jonas Reeb,David W. Ritchie,Sabeur Aridhi,Seyed Ziaeddin Alborzi,Seyed Ziaeddin Alborzi,Marie-Dominique Devignes,Marie-Dominique Devignes,Da Chen Emily Koo,Richard Bonneau,Vladimir Gligorijević,Meet Barot,Hai Fang,Stefano Toppo,Enrico Lavezzo,Marco Falda,Michele Berselli,Silvio C. E. Tosatto,Marco Carraro,Damiano Piovesan,Hafeez Ur Rehman,Qizhong Mao,Qizhong Mao,Shanshan Zhang,Slobodan Vucetic,Gage S. Black,Dane Jo,Erica Suh,Jonathan B. Dayton,Dallas J. Larsen,Ashton Omdahl,Liam J. McGuffin,Danielle A Brackenridge,Patricia C. Babbitt,Jeffrey M. Yunes,Paolo Fontana,Feng Zhang,Shanfeng Zhu,Ronghui You,Zihan Zhang,Suyang Dai,Shuwei Yao,Weidong Tian,Weidong Tian,Renzhi Cao,Caleb Chandler,Miguel Amezola,Devon Johnson,Jia-Ming Chang,Wen-Hung Liao,Yi-Wei Liu,Stefano Pascarelli,Yotam Frank,Robert Hoehndorf,Maxat Kulmanov,Imane Boudellioua,Gianfranco Politano,Stefano Di Carlo,Alfredo Benso,Kai Hakala,Filip Ginter,Farrokh Mehryary,Suwisa Kaewphan,Suwisa Kaewphan,Jari Björne,Jari Björne,Hans Moen,Martti Tolvanen,Tapio Salakoski,Tapio Salakoski,Daisuke Kihara,Daisuke Kihara,Aashish Jain,Tomislav Šmuc,Adrian M. Altenhoff,Adrian M. Altenhoff,Asa Ben-Hur,Burkhard Rost,Steven E. Brenner,Christine A. Orengo,Constance J. Jeffery,Giovanni Bosco,Deborah A. Hogan,Maria Jesus Martin,Claire O'Donovan,Sean D. Mooney,Casey S. Greene,Predrag Radivojac,Iddo Friedberg +188 more
TL;DR: The third CAFA challenge, CAFA3, that featured an expanded analysis over the previous CAFA rounds, both in terms of volume of data analyzed and the types of analysis performed, concluded that while predictions of the molecular function and biological process annotations have slightly improved over time, those of the cellular component have not.
Posted ContentDOI
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Naihui Zhou,Yuxiang Jiang,Timothy Bergquist,Alexandra J. Lee,Balint Z. Kacsoh,Alex W. Crocker,Kimberley A. Lewis,George Georghiou,Huy N Nguyen,Nafiz Hamid,Larry Davis,Tunca Doğan,Tunca Doğan,Volkan Atalay,Ahmet Sureyya Rifaioglu,Alperen Dalkiran,Rengul Cetin-Atalay,Chengxin Zhang,Rebecca L. Hurto,Peter L. Freddolino,Yang Zhang,Prajwal Bhat,Fran Supek,José M. Fernández,Branislava Gemovic,Vladimir Perovic,Radoslav Davidovic,Neven Sumonja,Nevena Veljkovic,Ehsaneddin Asgari,Mohammad R. K. Mofrad,Giuseppe Profiti,Giuseppe Profiti,Castrense Savojardo,Pier Luigi Martelli,Rita Casadio,Florian Boecker,Indika Kahanda,Natalie Thurlby,Alice C. McHardy,Alexandre Renaux,Alexandre Renaux,Rabie Saidi,Julian Gough,Alex A. Freitas,Magdalena Antczak,Fabio Fabris,Mark N. Wass,Jie Hou,Jianlin Cheng,Zheng Wang,Alfonso E. Romero,Alberto Paccanaro,Haixuan Yang,Tatyana Goldberg,Chenguang Zhao,Liisa Holm,Petri Törönen,Alan Medlar,Elaine Zosa,Itamar Borukhov,Ilya Novikov,Angela D. Wilkins,Olivier Lichtarge,Po-Han Chi,Wei-Cheng Tseng,Michal Linial,Peter W. Rose,Christophe Dessimoz,Christophe Dessimoz,Vedrana Vidulin,Saso Dzeroski,Ian Sillitoe,Sayoni Das,Jonathan G. Lees,Jonathan G. Lees,David T. Jones,David T. Jones,Cen Wan,Cen Wan,Domenico Cozzetto,Domenico Cozzetto,Rui Fa,Rui Fa,Mateo Torres,Alex Warwick Vesztrocy,Alex Warwick Vesztrocy,Jose Manuel Rodriguez,Michael L. Tress,Marco Frasca,Marco Notaro,Giuliano Grossi,Alessandro Petrini,Matteo Re,Giorgio Valentini,Marco Mesiti,Daniel B. Roche,Jonas Reeb,David W. Ritchie,Sabeur Aridhi,Seyed Ziaeddin Alborzi,Marie-Dominique Devignes,Da Chen Emily Koo,Richard Bonneau,Vladimir Gligorijević,Meet Barot,Hai Fang,Stefano Toppo,Enrico Lavezzo,Marco Falda,Michele Berselli,Silvio C. E. Tosatto,Marco Carraro,Damiano Piovesan,Hafeez Ur Rehman,Qizhong Mao,Qizhong Mao,Shanshan Zhang,Slobodan Vucetic,Gage S. Black,Dane Jo,Dallas J. Larsen,Ashton Omdahl,Luke W Sagers,Erica Suh,Jonathan B. Dayton,Liam J. McGuffin,Danielle A Brackenridge,Patricia C. Babbitt,Jeffrey M. Yunes,Paolo Fontana,Feng Zhang,Shanfeng Zhu,Ronghui You,Zihan Zhang,Suyang Dai,Shuwei Yao,Weidong Tian,Renzhi Cao,Caleb Chandler,Miguel Amezola,Devon Johnson,Jia-Ming Chang,Wen-Hung Liao,Yi-Wei Liu,Stefano Pascarelli,Yotam Frank,Robert Hoehndorf,Maxat Kulmanov,Imane Boudellioua,Gianfranco Politano,Stefano Di Carlo,Alfredo Benso,Kai Hakala,Filip Ginter,Farrokh Mehryary,Suwisa Kaewphan,Suwisa Kaewphan,Jari Björne,Jari Björne,Hans Moen,Martti Tolvanen,Tapio Salakoski,Tapio Salakoski,Daisuke Kihara,Daisuke Kihara,Aashish Jain,Tomislav Šmuc,Adrian M. Altenhoff,Asa Ben-Hur,Burkhard Rost,Steven E. Brenner,Christine A. Orengo,Constance J. Jeffery,Giovanni Bosco,Deborah A. Hogan,Maria Jesus Martin,Claire O'Donovan,Sean D. Mooney,Casey S. Greene,Predrag Radivojac,Iddo Friedberg +181 more
TL;DR: It is reported that the CAFA community now involves a broad range of participants with expertise in bioinformatics, biological experimentation, biocuration, and bioontologies, working together to improve functional annotation, computational function prediction, and the ability to manage big data in the era of large experimental screens.
Journal ArticleDOI
Identification of Patient Zero in Static and Temporal Networks: Robustness and Limitations
TL;DR: The statistical inference problem of detecting the source of epidemics from a snapshot of spreading on an arbitrary network structure is studied and the detectability limits for the susceptible-infected-recovered model, which primarily depend on the spreading process characteristics are demonstrated.