T
Tony Chao
Researcher at United States Department of the Army
Publications - 27
Citations - 1519
Tony Chao is an academic researcher from United States Department of the Army. The author has contributed to research in topics: Burn injury & Hypermetabolism. The author has an hindex of 13, co-authored 24 publications receiving 1259 citations. Previous affiliations of Tony Chao include Shriners Hospitals for Children - Galveston & University of Texas Medical Branch.
Papers
More filters
Journal ArticleDOI
Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans
Maria Chondronikola,Elena Volpi,Elisabet Børsheim,Craig Porter,Craig Porter,Palam Annamalai,Sven Enerbäck,Martin E. Lidell,Manish Kumar Saraf,Manish Kumar Saraf,Sébastien M. Labbé,Nicholas M. Hurren,Nicholas M. Hurren,Christina Yfanti,Tony Chao,Clark R. Andersen,Clark R. Andersen,Fernando Cesani,Hal K. Hawkins,Labros S. Sidossis +19 more
TL;DR: The results demonstrate a physiologically significant role of BAT in whole-body energy expenditure, glucose homeostasis, and insulin sensitivity in humans, and support the notion that BAT may function as an antidiabetic tissue in humans.
Journal ArticleDOI
Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans
Maria Chondronikola,Elena Volpi,Elisabet Børsheim,Elisabet Børsheim,Craig Porter,Craig Porter,Manish Kumar Saraf,Manish Kumar Saraf,Palam Annamalai,Christina Yfanti,Christina Yfanti,Tony Chao,Tony Chao,Daniel Wong,Kosaku Shinoda,Sebastien M. Labbė,Nicholas M. Hurren,Nicholas M. Hurren,Fernardo Cesani,Shingo Kajimura,Labros S. Sidossis +20 more
TL;DR: The accelerated mobilization and oxidation of lipids upon BAT activation supports a putative role for BAT in the regulation of lipid metabolism in humans.
Journal ArticleDOI
Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress (1160.5)
Labros S. Sidossis,Craig Porter,Manish Kumar Saraf,Tony Chao,Celeste C. Finnerty,Maria Chondronikola,Elisabet Børsheim,Hal K. Hawkins,David N. Herndon +8 more
TL;DR: In this paper, the authors investigated whether the WAT of humans has the capacity to adopt a BAT-like phenotype (browning of WAT) after severely burned children (early group [8±4 days post injury] or late group [37±25 days]) and 6 healthy children (control group).
Journal ArticleDOI
Human and Mouse Brown Adipose Tissue Mitochondria Have Comparable UCP1 Function.
Craig Porter,Craig Porter,David N. Herndon,David N. Herndon,Maria Chondronikola,Tony Chao,Tony Chao,Palam Annamalai,Nisha Bhattarai,Nisha Bhattarai,Manish Kumar Saraf,Manish Kumar Saraf,Karel D. Capek,Karel D. Capek,Paul T. Reidy,Alexes C. Daquinag,Mikhail G. Kolonin,Blake B. Rasmussen,Elisabet Børsheim,Tracy Toliver-Kinsky,Labros S. Sidossis,Labros S. Sidossis +21 more
TL;DR: Human BAT was sensitive to the purine nucleotide GDP, providing the first direct evidence that human BAT mitochondria have thermogenically functional UCP1, and data demonstrate that human and rodent BAT have similar U CP1 function per mitochondrion.
Journal ArticleDOI
Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults
Craig Porter,David N. Herndon,Elisabet Børsheim,Tony Chao,Paul T. Reidy,Michael S. Borack,Blake B. Rasmussen,Maria Chondronikola,Manish Kumar Saraf,Labros S. Sidossis +9 more
TL;DR: It is hypothesized that uncoupling of oxidative phosphorylation in skeletal muscle mitochondria contributes to increased metabolic rate in burn survivors, and skeletal muscle mitochondrial function in healthy and severely burned adults is determined.