T
Tonya S. King
Researcher at Pennsylvania State University
Publications - 90
Citations - 4616
Tonya S. King is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Asthma & Concordance correlation coefficient. The author has an hindex of 32, co-authored 82 publications receiving 4067 citations. Previous affiliations of Tonya S. King include University of Kentucky & United States Public Health Service.
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Journal ArticleDOI
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.
Yvonne J. Huang,Craig E. Nelson,Eoin L. Brodie,Todd Z. DeSantis,Marshall S. Baek,Jane Liu,Tanja Woyke,Martin Allgaier,James Bristow,Jeanine P. Wiener-Kronish,E. Rand Sutherland,Tonya S. King,Nikolina Icitovic,Richard J. Martin,William J. Calhoun,Mario Castro,Loren C. Denlinger,Emily DiMango,Monica Kraft,Stephen P. Peters,Stephen I. Wasserman,Michael E. Wechsler,Homer A. Boushey,Susan V. Lynch +23 more
TL;DR: The composition of Bronchial airway microbiota is associated with the degree of bronchial hyperresponsiveness among patients with suboptimally controlled asthma, and these findings support the need for further functional studies to examine the potential contribution of members of theAirway microbiota in asthma pathogenesis.
Journal ArticleDOI
Daily versus As-Needed Corticosteroids for Mild Persistent Asthma
Homer A. Boushey,Christine A. Sorkness,Tonya S. King,Sean D. Sullivan,John V. Fahy,Stephen C. Lazarus,Vernon M. Chinchilli,Timothy J. Craig,Emily A. Dimango,Aaron Deykin,Joanne K. Fagan,James E. Fish,Jean G. Ford,Monica Kraft,Robert F. Lemanske,Frank T. Leone,Richard J. Martin,Elizabeth A. Mauger,Gene R. Pesola,Stephen P. Peters,Nancy J. Rollings,Stanley J. Szefler,Michael E. Wechsler,Elliot Israel +23 more
TL;DR: It may be possible to treat mild persistent asthma with short, intermittent courses of inhaled or oral corticosteroids taken when symptoms worsen, and further studies are required to determine whether this novel approach to treatment should be recommended.
Journal ArticleDOI
Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.
Mario Castro,Tonya S. King,Susan J. Kunselman,Michael D. Cabana,Loren C. Denlinger,Fernando Holguin,Shamsah Kazani,Wendy C. Moore,James N. Moy,Christine A. Sorkness,Pedro C. Avila,Leonard B. Bacharier,Eugene R. Bleecker,Homer A. Boushey,James F. Chmiel,Anne M. Fitzpatrick,Deborah A. Gentile,Mandeep Hundal,Elliot Israel,Monica Kraft,Jerry A. Krishnan,Craig LaForce,Stephen C. Lazarus,Robert F. Lemanske,Njira L Lugogo,Richard J. Martin,David T. Mauger,Edward T. Naureckas,Stephen P. Peters,Wanda Phipatanakul,Loretta G. Que,Ajay Sheshadri,Lewis J. Smith,Julian Solway,Lisa Sullivan-Vedder,Kaharu Sumino,Michael E. Wechsler,Sally E. Wenzel,Steven R. White,E. Rand Sutherland +39 more
TL;DR: Vitamin D3 did not reduce the rate of first treatment failure or exacerbation in adults with persistent asthma and vitamin D insufficiency, and findings do not support a strategy of therapeutic vitamin D3 supplementation in patients with symptomatic asthma.
Journal ArticleDOI
Cluster Analysis of Obesity and Asthma Phenotypes
E. Rand Sutherland,Elena Goleva,Tonya S. King,Erik Lehman,Allen D. Stevens,Leisa P. Jackson,Amanda R. Stream,John V. Fahy +7 more
TL;DR: Members of obese clusters demonstrated evidence of reduced expression of GCRα, a finding which was correlated with a reduced induction of MKP-1 expression by dexamethasone, which may mediate GC insensitivity in obese asthmatics.
Journal ArticleDOI
The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial.
Richard J. Martin,Stanley J. Szefler,Tonya S. King,Monica Kraft,Homer A. Boushey,Vernon M. Chinchilli,Timothy J. Craig,Emily A. Dimango,Aaron Deykin,John V. Fahy,Elliot Israel,Stephen C. Lazarus,Robert F. Lemanske,Frank T. Leone,Gene R. Pesola,Stephen P. Peters,Christine A. Sorkness,Lisa A. Szwejbka,Michael E. Wechsler +18 more
TL;DR: The short-term response to inhaled corticosteroids with regard to FEV(1) improvement predicts long-term asthma control, and different therapeutic strategies would need to be established for nonresponders.