T
Toshiaki Furuta
Researcher at Toho University
Publications - 98
Citations - 4045
Toshiaki Furuta is an academic researcher from Toho University. The author has contributed to research in topics: Bicyclic molecule & Protecting group. The author has an hindex of 29, co-authored 95 publications receiving 3843 citations. Previous affiliations of Toshiaki Furuta include University of California & Center for Advanced Materials.
Papers
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Journal ArticleDOI
Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting groups with biologically useful cross-sections for two photon photolysis
Toshiaki Furuta,Samuel S.-H. Wang,Jami L. Dantzker,Timothy M. Dore,Wendy J. Bybee,Edward M. Callaway,Winfried Denk,Roger Y. Tsien +7 more
TL;DR: It is shown that brominated 7-hydroxycoumarin-4-ylmethyl esters and carbamates efficiently release carboxylates and amines on photolysis, with one- and two-photon cross sections up to one or two orders of magnitude better than previously available.
Journal Article
Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting groups with biologically useful cross-sections for two photon photolysis
Toshiaki Furuta,Samuel S.-H. Wang,Jami L. Dantzker,Timothy M. Dore,Wendy J. Bybee,Edward M. Callaway,Winfried Denk,Roger Y. Tsien +7 more
TL;DR: In this paper, the authors showed that brominated 7-hydroxycoumarin-4-ylmethyl esters and carbamates efficiently release carboxylates and amines on photolysis, with one and two-photon cross sections up to one or two orders of magnitude better than previously available.
Journal ArticleDOI
Photo-mediated gene activation using caged RNA/DNA in zebrafish embryos
TL;DR: It is shown that uncaging eng2a in the head region during early development causes a severe reduction in the size of the eye and enhanced development of the mid brain and the midbrain-hindbrain boundary at the expense of the forebrain.
Journal ArticleDOI
Photo-Induced Peptide Cleavage in the Green-to-Red Conversion of a Fluorescent Protein
Hideaki Mizuno,Tapas K. Mal,Kit I. Tong,Ryoko Ando,Toshiaki Furuta,Mitsuhiko Ikura,Atsushi Miyawaki +6 more
TL;DR: The present study not only reveals diversity in the chemical structure of fluorescent proteins but also adds a new dimension to posttranslational modification mechanisms.
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Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells.
TL;DR: The data identify a DAG-dependent pathway that signals through dynein to control microtubule polarity in T cells and shows that MTOC polarization is driven by localized accumulation of diacylglycerol (DAG).