T
Toshihiko Takada
Researcher at Utrecht University
Publications - 80
Citations - 4052
Toshihiko Takada is an academic researcher from Utrecht University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 63 publications receiving 2724 citations. Previous affiliations of Toshihiko Takada include Chiba University & Kyoto University.
Papers
More filters
Journal ArticleDOI
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal
Laure Wynants,Laure Wynants,Ben Van Calster,Ben Van Calster,Gary S. Collins,Gary S. Collins,Richard D Riley,Georg Heinze,Ewoud Schuit,Marc J.M. Bonten,Darren Dahly,Johanna A A G Damen,Thomas P. A. Debray,Valentijn M.T. de Jong,Maarten De Vos,Paula Dhiman,Paula Dhiman,Maria C Haller,Michael O. Harhay,Liesbet Henckaerts,Pauline Heus,Michael Kammer,Nina Kreuzberger,Anna Lohmann,Kim Luijken,Jie Ma,Glen P. Martin,David J. McLernon,Constanza L Andaur Navarro,Johannes B. Reitsma,Jamie C. Sergeant,Chunhu Shi,Nicole Skoetz,Luc J.M. Smits,Kym I E Snell,Matthew Sperrin,René Spijker,René Spijker,Ewout W. Steyerberg,Toshihiko Takada,Ioanna Tzoulaki,Ioanna Tzoulaki,Sander M. J. van Kuijk,Bas C T van Bussel,Bas C T van Bussel,Iwan C. C. van der Horst,Florien S. van Royen,Jan Y Verbakel,Jan Y Verbakel,Christine Wallisch,Christine Wallisch,Jack Wilkinson,Robert Wolff,Lotty Hooft,Karel G.M. Moons,Maarten van Smeden +55 more
TL;DR: Proposed models for covid-19 are poorly reported, at high risk of bias, and their reported performance is probably optimistic, according to a review of published and preprint reports.
Journal ArticleDOI
Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.
Hiromasa Takaishi,Takahiro Matsuki,Atsushi Nakazawa,Toshihiko Takada,Shoichi Kado,Takashi Asahara,Nobuhiko Kamada,Atsushi Sakuraba,Tomoharu Yajima,Hajime Higuchi,Nagamu Inoue,Haruhiko Ogata,Yasushi Iwao,Koji Nomoto,Ryuichiro Tanaka,Toshifumi Hibi +15 more
TL;DR: Findings indicate that IBD is not caused by a specific intestinal bacterial cluster or species and that disordered intestinal microflora could be involved in the pathogenesis of IBD.
Journal ArticleDOI
Establishment of an analytical system for the human fecal microbiota, based on reverse transcription-quantitative PCR targeting of multicopy rRNA molecules.
Kazunori Matsuda,Hirokazu Tsuji,Takashi Asahara,Kazumasa Matsumoto,Toshihiko Takada,Koji Nomoto +5 more
TL;DR: The results suggest that RT-qPCR is effective for the accurate enumeration of human intestinal microbiota, especially the entire analysis of both predominant and subdominant populations.
Journal ArticleDOI
Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
Satoshi Matsumoto,Taeko Hara,Keiichi Mitsuyama,Mayuko Yamamoto,Osamu Tsuruta,Michio Sata,Jürgen Scheller,Stefan Rose-John,Shoichi Kado,Toshihiko Takada +9 more
TL;DR: IL-6 trans-signaling in epithelial cells induced by macrophage-derived IL-6/sIL- 6Rα plays a crucial role in the development of CAC.
Journal ArticleDOI
Effects of a probiotic fermented milk beverage containing Lactobacillus casei strain Shirota on defecation frequency, intestinal microbiota, and the intestinal environment of healthy individuals with soft stools.
Kazumasa Matsumoto,Toshihiko Takada,Kensuke Shimizu,Kaoru Moriyama,Koji Kawakami,Koichi Hirano,Osami Kajimoto,Koji Nomoto +7 more
TL;DR: It is suggested that probiotic fermented milk beverage has an intestine-conditioning effect by improving the frequency of defecation and stool quality and increasing the intrinsic bifidobacteria in healthy individuals with soft stool.