T
Toshio Fukai
Researcher at Toho University
Publications - 154
Citations - 4337
Toshio Fukai is an academic researcher from Toho University. The author has contributed to research in topics: Bark & Glycyrrhiza. The author has an hindex of 35, co-authored 154 publications receiving 4080 citations. Previous affiliations of Toshio Fukai include Kunming Institute of Botany & Meikai University.
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Anti-Helicobacter pylori flavonoids from licorice extract.
TL;DR: Three new isoflavonoids with a pyran ring, gancaonols A[bond]C, were isolated together with 15 known flavonoids and exhibited anti-H.
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Hypoglycemic effect of Egyptian Morus alba root bark extract : Effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats
TL;DR: The data obtained from this study revealed that MRBF-3 may protect pancreatic beta cells from degeneration and diminish lipid peroxidation, however, this is the first biological screening of the Egyptian Morus alba root bark; further future merit studies including clinical study will be necessary in order to confirm the results obtained.
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Cytotoxic flavonoids with isoprenoid groups from Morus mongolica
Ya-Qin Shi,Toshio Fukai,Hiroshi Sakagami,Wen-Jin Chang,Pei-Quan Yang,Feng-Peng Wang,Taro Nomura +6 more
TL;DR: All flavanones investigated here showed higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF) and the cytot toxicity of compound 2 and the Diels-Alder type flavanone sanggenon C isolated from Morus cathayana were the most potent.
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Antimicrobial activity of licorice flavonoids against methicillin-resistant Staphylococcus aureus.
TL;DR: Nineteen flavonoids isolated from licorice were tested for their antimicrobial activities against methicillin sensitive Staphylococcus aureus, methamphetamineicillin resistant S. aureUS, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa.
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Chemistry of phenolic compounds of licorice (Glycyrrhiza species) and their estrogenic and cytotoxic activities
TL;DR: In the course of screening phytoestrogen in medicinal plants, six Glycyrrhiza phenols exhibited the binding affinities for the bovine uterine estrogen receptor, and the affinity of a dihydrostilbene with two 3-methyl-2-butenyl (prenyl) groups, gancaonin R, was higher than those of isoflavone phy toestrogens in dietary foods.