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Toshio Morikawa

Researcher at Kindai University

Publications -  314
Citations -  11562

Toshio Morikawa is an academic researcher from Kindai University. The author has contributed to research in topics: Triterpene & Salacia. The author has an hindex of 61, co-authored 299 publications receiving 10434 citations. Previous affiliations of Toshio Morikawa include China Pharmaceutical University & Kyoto Pharmaceutical University.

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Journal ArticleDOI

Carnosic acid, a new class of lipid absorption inhibitor from sage

Kiyofumi Ninomiya, +7 more
- 19 Apr 2004 - 
TL;DR: Carnosic acid significantly inhibited triglyceride elevation in olive oil-loaded mice at doses of 5-20 mg/kg (p.o.) and reduced the gain of body weight and the accumulation of epididymal fat weight in high fat diet-fed mice after 14 days.
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Structural Requirements of Flavonoids and Related Compounds for Aldose Reductase Inhibitory Activity

Hisashi Matsuda, +3 more
- 01 Jun 2002 - 
TL;DR: The methanolic extracts of several natural medicines and medicinal foodstuffs were found to show an inhibitory effect on rat lens aldose reductase, and various flavonoids and related compounds were examined to clarify the structural requirements of flavonoidal activity.
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Structural requirements of flavonoids for nitric oxide production inhibitory activity and mechanism of action.

Hisashi Matsuda, +4 more
- 01 May 2003 - 
TL;DR: Strong inhibitory effects of flavonoids on NO production in lipopolysaccharide-activated mouse peritoneal macrophages were examined and potent NO production inhibitors were found to inhibit induction of inducible nitric oxide synthase without iNOS enzymatic inhibitory activity.
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Absolute Stereostructure of Potent α-Glucosidase Inhibitor, Salacinol, with Unique Thiosugar Sulfonium Sulfate Inner Salt Structure from Salacia reticulata

Masayuki Yoshikawa, +4 more
- 01 May 2002 - 
TL;DR: Salacinol showed potent inhibitory activities on several alpha-glucosidases, such as maltase, sucrase, and isomaltases, and the inhibitory effects on serum glucose levels in maltose- and sucrose-loaded rats (in vivo) were found to be more potent than that of acarbose, a commercial alpha- GLUCosidase inhibitor.
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Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.

Hisashi Matsuda, +5 more
- 01 Jan 2001 - 
TL;DR: The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and .O2- and several stilbenes with both the 3-hydroxyl and 4'-methoxyl groups inhibited xanthine oxidase.