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Toshio Narahashi

Researcher at Northwestern University

Publications -  247
Citations -  11637

Toshio Narahashi is an academic researcher from Northwestern University. The author has contributed to research in topics: Sodium channel & Patch clamp. The author has an hindex of 58, co-authored 247 publications receiving 11281 citations. Previous affiliations of Toshio Narahashi include Marine Biological Laboratory & University of California, Santa Cruz.

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Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons

Mary Louise Roy, +1 more
- 01 Jun 1992 - 
TL;DR: TTX-sensitive and TTX-resistant sodium channel currents were analyzed in acutely dissociated dorsal root ganglion (DRG) neurons isolated from 3–12-d-old and adult rats, and several external divalent cations exerted different effects on these current types.
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Neuronal Ion Channels as the Target Sites of Insecticides

Toshio Narahashi
- 01 Jul 1996 - 
TL;DR: It appears that the sodium channel and the GABA system merit continuing efforts for development of newer and better insecticides.
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Characterization of two types of calcium channels in mouse neuroblastoma cells.

Toshio Narahashi, +2 more
- 01 Feb 1987 - 
TL;DR: Calcium channel currents as carried by Ba2+ (50 mM) were recorded using the whole‐cell variation of the patch‐electrode voltage‐clamp technique and were considered to be two different entities, equally sensitive to the temperature.
Journal Article

Neuroreceptors and ion channels as the basis for drug action: past, present, and future.

Toshio Narahashi
- 01 Jul 2000 - 
TL;DR: This article summarizes the development of cellular neuropharmacology and neurotoxicology, based primarily on my own research, and emphasis is placed on the three-dimensional structure-activity relationship, in particular how changes in the molecular structure of drugs and receptors/channels result in kineticChanges in the function of receptors/Channels.
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Kinetics of sodium channel modification as the basis for the variation in the nerve membrane effects of pyrethroids and DDT analogs

Albert E. Lund, +1 more
- 01 Oct 1983 - 
TL;DR: The effects of the phenoxybenzyl pyrethroids were found to be intermediate between these two extremes suggesting that a continuous variation exists in kinetics with which pyre Throids and DDT analogs modify sodium channels.