Travis R. Blum

TL;DR: This Review summarizes dual-catalyst strategies that have been applied to synthetic photochemistry, and focuses upon the cooperative interactions of photocatalysts with redox mediators, Lewis and Brønsted acids, organocatalyst, enzymes, and transition metal complexes.

TL;DR: The discovery that a chiral Lewis acid complex can catalyze triplet energy transfer from an electronically excited photosensitizer is reported, and it is expected that this approach will enable chemists to more broadly apply their detailed understanding of chiralLewis acid catalysis to stereocontrol in reactions involving electronically excited states.

TL;DR: Visible-light-activated transition metal photocatalysis enables the use of ammonium persulfate as an easily handled, benign terminal oxidant in oxidative cycloadditions of phenols and alkenes applicable to the modular synthesis of a large family of dihydrobenzofuran natural products.

TL;DR: The authors developed a phage-assisted protease evolution system with simultaneous positive and negative selection and applied it to three botulinum neurotoxin (BoNT) light-chain proteases.

TL;DR: This synthetic route, well-suited to SAR, represents a generalizable route toward all manner of analogs, including structures with acidic and basic amino acids.