T
Trevor W. Robbins
Researcher at University of Cambridge
Publications - 1184
Citations - 177352
Trevor W. Robbins is an academic researcher from University of Cambridge. The author has contributed to research in topics: Prefrontal cortex & Cognition. The author has an hindex of 231, co-authored 1137 publications receiving 164437 citations. Previous affiliations of Trevor W. Robbins include Centre national de la recherche scientifique & Massachusetts Institute of Technology.
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Journal ArticleDOI
Effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on visual discrimination acquisition, performance and reversal in the rat.
J. L. Evenden,H.M. Marston,Graham H. Jones,V. Giardini,László Lénárd,Barry J. Everitt,Trevor W. Robbins +6 more
TL;DR: It is concluded that ibotenic acid lesions of the substantia innominata or to the dorsal globus pallidus affect learning and performance of conditional visual discrimination performance and impair reversal learning without affecting the capacity to discriminate visual events.
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Cocaine dependence: a fast-track for brain ageing?
Karen D. Ersche,P.S. Jones,Guy B. Williams,Trevor W. Robbins,Edward T. Bullmore,Edward T. Bullmore,Edward T. Bullmore +6 more
TL;DR: In this paper, the effects of age on gray matter volume in 120 individuals aged 18-50 years were compared with healthy volunteers and 60 cocaine-dependent individuals, and the two groups were matched for age (t118=−0.12, p=0.905), gender (χ2=2.8, P= 0.148), and verbal IQ (t115=− 0.36, P = 0.031).
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Markers of Serotonergic Function in the Orbitofrontal Cortex and Dorsal Raphé Nucleus Predict Individual Variation in Spatial-Discrimination Serial Reversal Learning
Rebecca L Barlow,Johan Alsiö,Bianca Jupp,Rebecca Rabinovich,Saurav Shrestha,Angela C. Roberts,Trevor W. Robbins,Jeffrey W. Dalley +7 more
TL;DR: Findings indicate that diminished serotonergic tone in the OFC may be an endophenotype that predisposes to behavioral inflexibility and other forms of compulsive behavior.
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The dopamine D2 receptor antagonist sulpiride modulates striatal BOLD signal during the manipulation of information in working memory.
Chris M. Dodds,Luke Clark,Anja Dove,Ralf Regenthal,Frank Baumann,Edward T. Bullmore,Trevor W. Robbins,Ulrich Müller +7 more
TL;DR: These results support models of dopamine function that posit a ‘gating’ function for dopamine D2 receptors in the striatum, which enables the flexible updating and manipulation of information in working memory.
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Homology in behavioural pharmacology: an approach to animal models of human cognition.
TL;DR: It is suggested that known correspondences across species in brain structure and development which may mediate homologous behavioural functions are capitalize on, and Manipulation of specific receptors in defined areas may be achieved by local and systemic administration of drugs with relatively specific actions.